selected publications
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academic article
- Distribution of cerebral microbleeds in the East and West: Individual participant meta-analysis.. Neurology. 92:e1086-e1097. 2019
- Baseline White Matter Hyperintensities and Hippocampal Volume are Associated With Conversion From Normal Cognition to Mild Cognitive Impairment in the Framingham Offspring Study.. Alzheimer disease and associated disorders. 32:50-56. 2018
- Overweight, Obesity, and Survival After Stroke in the Framingham Heart Study.. Journal of the American Heart Association. 6. 2017
- Association of descending thoracic aortic plaque with brain atrophy and white matter hyperintensities: The Framingham Heart Study.. Atherosclerosis. 305-311. 2017
- Revised Framingham Stroke Risk Profile to Reflect Temporal Trends.. Circulation. 135:1145-1159. 2017
- Cerebral Microbleeds as Predictors of Mortality: The Framingham Heart Study.. Stroke. 48:781-783. 2017
- Stroke as the Initial Manifestation of Atrial Fibrillation: The Framingham Heart Study.. Stroke. 48:490-492. 2017
- Overweight, Obesity, and Survival After Stroke in the Framingham Heart Study. Journal of the American Heart Association. 2017
- Revised Framingham Stroke Risk Profile to Reflect Temporal TrendsClinical Perspective. Circulation. 2017
- Circulating biomarkers and incident ischemic stroke in the Framingham Offspring Study.. Neurology. 87:1206-11. 2016
- Association between atrial fibrillation and volumetric magnetic resonance imaging brain measures: Framingham Offspring Study.. Heart rhythm. 13:2020-4. 2016
- Interaction Between Midlife Blood Glucose and APOE Genotype Predicts Later Alzheimer's Disease Pathology.. Journal of Alzheimer's disease : JAD. 53:1553-62. 2016
- Carotid Atherosclerosis and Cerebral Microbleeds: The Framingham Heart Study.. Journal of the American Heart Association. 5:-. 2016
- Pulse Pressure Is Associated With Early Brain Atrophy and Cognitive Decline: Modifying Effects of APOE-ε4.. Alzheimer disease and associated disorders. 30:210-5. 2016
- Evaluation of power of the Illumina HumanOmni5M-4v1 BeadChip to detect risk variants for human complex diseases.. European journal of human genetics : EJHG. 24:1029-34. 2015
- Spectrum of cognition short of dementia: Framingham Heart Study and Mayo Clinic Study of Aging.. Neurology. 85:1712-21. 2015
- 50 year trends in atrial fibrillation prevalence, incidence, risk factors, and mortality in the Framingham Heart Study: a cohort study.. Lancet (London, England). 386:154-62. 2015
- Glucose indices are associated with cognitive and structural brain measures in young adults.. Neurology. 84:2329-37. 2015
- Long-term exposure to fine particulate matter, residential proximity to major roads and measures of brain structure.. Stroke. 46:1161-6. 2015
- Verbal memory and brain aging: an exploratory analysis of the role of error responses in the Framingham Study.. American journal of Alzheimer's disease and other dementias. 30:622-8. 2015
- Low cardiac index is associated with incident dementia and Alzheimer disease: the Framingham Heart Study.. Circulation. 131:1333-9. 2015
- Inflammatory biomarkers, cerebral microbleeds, and small vessel disease: Framingham Heart Study.. Neurology. 84:825-32. 2015
- Lipid and lipoprotein measurements and the risk of ischemic vascular events: Framingham Study.. Neurology. 84:472-9. 2015
- Mid-life Cardiovascular Risk Impacts Memory Function: The Framingham Offspring Study.. Alzheimer disease and associated disorders. 29:117-23. 2015
- Midlife Hypertension Risk and Cognition in the Non-Demented Oldest Old: Framingham Heart Study.. Journal of Alzheimer's disease : JAD. 47:197-204. 2015
- Normative Data for the Cognitively Intact Oldest-Old: The Framingham Heart Study.. Experimental aging research. 41:386-409. 2015
- APOE and mild cognitive impairment: the Framingham Heart Study.. Age and ageing. 44:307-11. 2014
- Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium.. Biological psychiatry. 77:749-63. 2014
- Plasma amyloid-β and risk of Alzheimer's disease in the Framingham Heart Study.. Alzheimer's & dementia : the journal of the Alzheimer's Association. 11:249-57.e1. 2014
- Associations of NINJ2 sequence variants with incident ischemic stroke in the Cohorts for Heart and Aging in Genomic Epidemiology (CHARGE) consortium.. PloS one. 9:-. 2014
- Cognitive performance after stroke--the Framingham Heart Study.. International journal of stroke : official journal of the International Stroke Society. 9 Suppl A100:48-54. 2014
- Risk factors, stroke prevention treatments, and prevalence of cerebral microbleeds in the Framingham Heart Study.. Stroke. 45:1492-4. 2014
- Insulin-like growth factor-1 and risk of Alzheimer dementia and brain atrophy.. Neurology. 82:1613-9. 2014
- Predicting stroke through genetic risk functions: the CHARGE Risk Score Project.. Stroke. 45:403-12. 2014
- Gender and incidence of dementia in the Framingham Heart Study from mid-adult life.. Alzheimer's & dementia : the journal of the Alzheimer's Association. 11:310-320. 2014
- Association between neuropathology and brain volume in the Framingham Heart Study.. Alzheimer disease and associated disorders. 28:219-25. 2014
- Serum brain-derived neurotrophic factor and the risk for dementia: the Framingham Heart Study.. JAMA neurology. 71:55-61. 2014
- Parental longevity is associated with cognition and brain ageing in middle-aged offspring.. Age and ageing. 43:358-63. 2013
- Neck circumference, carotid wall intima-media thickness, and incident stroke.. Diabetes care. 36:e153-4. 2013
- APOE genotype and MRI markers of cerebrovascular disease: systematic review and meta-analysis.. Neurology. 81:292-300. 2013
- Transient global amnesia and neurological events: the framingham heart study.. Frontiers in neurology. -. 2013
- Association of parental stroke with brain injury and cognitive measures in offspring: the Framingham Heart Study.. Stroke. 44:812-5. 2013
- Qualitative neuropsychological measures: normative data on executive functioning tests from the Framingham offspring study.. Experimental aging research. 39:515-35. 2013
- Risk estimations, risk factors, and genetic variants associated with Alzheimer's disease in selected publications from the Framingham Heart Study.. Journal of Alzheimer's disease : JAD. 33 Suppl 1:S439-45. 2013
- The Framingham Heart Study clock drawing performance: normative data from the offspring cohort.. Experimental aging research. 39:80-108. 2013
- Effects of systolic blood pressure on white-matter integrity in young adults in the Framingham Heart Study: a cross-sectional study.. The Lancet. Neurology. 11:1039-47. 2012
- Lipoprotein phospholipase A2 and cerebral microbleeds in the Framingham Heart Study.. Stroke. 43:3091-4. 2012
- The Framingham Brain Donation Program: neuropathology along the cognitive continuum.. Current Alzheimer research. 9:673-86. 2012
- Biomarkers for insulin resistance and inflammation and the risk for all-cause dementia and alzheimer disease: results from the Framingham Heart Study.. Archives of neurology. 69:594-600. 2012
- Common variants at 12q14 and 12q24 are associated with hippocampal volume.. Nature genetics. 44:545-51. 2012
- Common variants at 6q22 and 17q21 are associated with intracranial volume.. Nature genetics. 44:539-44. 2012
- Multiple biomarkers and risk of clinical and subclinical vascular brain injury: the Framingham Offspring Study.. Circulation. 125:2100-7. 2012
- Relation of left ventricular ejection fraction to cognitive aging (from the Framingham Heart Study).. The American journal of cardiology. 108:1346-51. 2011
- Large-scale candidate gene analysis in whites and African Americans identifies IL6R polymorphism in relation to atrial fibrillation: the National Heart, Lung, and Blood Institute's Candidate Gene Association Resource (CARe) project.. Circulation. Cardiovascular genetics. 4:557-64. 2011
- Apolipoprotein epsilon 4 allele modifies waist-to-hip ratio effects on cognition and brain structure.. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. 22:119-25. 2011
- Association of metabolic dysregulation with volumetric brain magnetic resonance imaging and cognitive markers of subclinical brain aging in middle-aged adults: the Framingham Offspring Study.. Diabetes care. 34:1766-70. 2011
- Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium.. Annals of neurology. 69:928-39. 2011
- Operationalizing diagnostic criteria for Alzheimer's disease and other age-related cognitive impairment-Part 2.. Alzheimer's & dementia : the journal of the Alzheimer's Association. 7:35-52. 2011
- Cardiac index is associated with brain aging: the Framingham Heart Study.. Circulation. 122:690-7. 2010
- Longitudinal genetic analysis of brain volumes in normal elderly male twins.. Neurobiology of aging. 33:636-44. 2010
- White matter hyperintensity and cognitive functioning in the racial and ethnic minority cohort of the Framingham Heart Study.. Neuroepidemiology. 35:117-22. 2010
- Association of matrix metalloproteinases with MRI indices of brain ischemia and aging.. Neurobiology of aging. 31:2128-35. 2009
- Thyroid function and the risk of Alzheimer disease: the Framingham Study.. Archives of internal medicine. 168:1514-20. 2008
- Association of plasma total homocysteine levels with subclinical brain injury: cerebral volumes, white matter hyperintensity, and silent brain infarcts at volumetric magnetic resonance imaging in the Framingham Offspring Study.. Archives of neurology. 65:642-9. 2008
- Lifetime risk of stroke and dementia: current concepts, and estimates from the Framingham Study.. The Lancet. Neurology. 6:1106-14. 2007
- Framingham Heart Study 100K project: genome-wide associations for cardiovascular disease outcomes.. BMC medical genetics. 8 Suppl 1:-. 2007
- Genetic correlates of brain aging on MRI and cognitive test measures: a genome-wide association and linkage analysis in the Framingham Study.. BMC medical genetics. 8 Suppl 1:-. 2007
- Relation of obesity to cognitive function: importance of central obesity and synergistic influence of concomitant hypertension. The Framingham Heart Study.. Current Alzheimer research. 4:111-6. 2007
- Left ventricular mass, blood pressure, and lowered cognitive performance in the Framingham offspring.. Hypertension (Dallas, Tex. : 1979). 49:439-45. 2007
- The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports.. BMC medical genetics. 8 Suppl 1:-. 2007
- Trends in incidence, lifetime risk, severity, and 30-day mortality of stroke over the past 50 years.. JAMA. 296:2939-46. 2006
- Diabetes mellitus and risk of developing Alzheimer disease: results from the Framingham Study.. Archives of neurology. 63:1551-5. 2006
- Association of white matter hyperintensity volume with decreased cognitive functioning: the Framingham Heart Study.. Archives of neurology. 63:246-50. 2006
- The lifetime risk of stroke: estimates from the Framingham Study.. Stroke. 37:345-50. 2006
- Atrial fibrillation is associated with lower cognitive performance in the Framingham offspring men.. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. 15:214-22. 2006
- Genome-wide scan for white matter hyperintensity: the Framingham Heart Study.. Stroke. 37:77-81. 2005
- Homocysteine and cognitive performance in the Framingham offspring study: age is important.. American journal of epidemiology. 162:644-53. 2005
- Measures of brain morphology and infarction in the framingham heart study: establishing what is normal.. Neurobiology of aging. 26:491-510. 2005
- Bone mineral density and the risk of Alzheimer disease.. Archives of neurology. 62:107-11. 2005
- Stroke risk profile predicts white matter hyperintensity volume: the Framingham Study.. Stroke. 35:1857-61. 2004
- Cerebral microbleeds: prevalence and associations with cardiovascular risk factors in the Framingham Study.. Stroke. 35:1831-5. 2004
- Genetic variation in white matter hyperintensity volume in the Framingham Study.. Stroke. 35:1609-13. 2004
- Dementia after stroke: the Framingham Study.. Stroke. 35:1264-8. 2004
- Managing and analysing data from a large-scale study on Framingham Offspring relating brain structure to cognitive function.. Statistics in medicine. 23:351-67. 2004
- Framingham stroke risk profile and lowered cognitive performance.. Stroke. 35:404-9. 2004
- New norms for a new generation: cognitive performance in the framingham offspring cohort.. Experimental aging research. 30:333-58. 2004
- Plasma total cholesterol level as a risk factor for Alzheimer disease: the Framingham Study.. Archives of internal medicine. 163:1053-7. 2003
- Homocysteine and the brain: vascular risk factor or neurotoxin?. The Lancet. Neurology. 2:-. 2003
- Plasma homocysteine as a risk factor for dementia and Alzheimer's disease.. The New England journal of medicine. 346:476-83. 2002
- Antecedent blood pressure and risk of cardiovascular disease: the Framingham Heart Study .. Circulation. 105:48-53. 2002