selected publications
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academic article
- Isoform- and cell type-specific structure of apolipoprotein E lipoparticles as revealed by a novel Forster resonance energy transfer assay.. The Journal of biological chemistry. 292:14720-14729. 2017
- Dynamic presenilin 1 and synaptotagmin 1 interaction modulates exocytosis and amyloid β production.. Molecular neurodegeneration. 12:-. 2017
- Pathogenic PS1 phosphorylation at Ser367.. eLife. 2017
- Identification of the novel activity-driven interaction between synaptotagmin 1 and presenilin 1 links calcium, synapse, and amyloid beta.. BMC biology. -. 2016
- Oxidative stress and lipid peroxidation are upstream of amyloid pathology.. Neurobiology of disease. 109-19. 2015
- Neuronal activity and secreted amyloid β lead to altered amyloid β precursor protein and presenilin 1 interactions.. Neurobiology of disease. 127-34. 2012
- Two postprocessing techniques for the elimination of background autofluorescence for fluorescence lifetime imaging microscopy.. Journal of biomedical optics. 13:-. 2008
- Interaction between presenilin 1 and ubiquilin 1 as detected by fluorescence lifetime imaging microscopy and a high-throughput fluorescent plate reader.. The Journal of biological chemistry. 281:26400-7. 2006
- Time-domain fluorescent plate reader for cell based protein-protein interaction and protein conformation assays.. Journal of biomedical optics. 11:-. 2006
- Designed helical peptides inhibit an intramembrane protease.. Journal of the American Chemical Society. 125:11794-5. 2003
- Monitoring proteins in intact cells.. Science of aging knowledge environment : SAGE KE. 2003:-. 2003
- Amyloid precursor protein associates with a nicastrin-dependent docking site on the presenilin 1-gamma-secretase complex in cells demonstrated by fluorescence lifetime imaging.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 23:4560-6. 2003
- Gamma-secretase/presenilin inhibitors for Alzheimer's disease phenocopy Notch mutations in Drosophila.. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 17:79-81. 2002
- The gamma secretase-generated carboxyl-terminal domain of the amyloid precursor protein induces apoptosis via Tip60 in H4 cells.. The Journal of biological chemistry. 277:28530-6. 2002