academic article

• Soluble oligomeric amyloid-β induces calcium dyshomeostasis that precedes synapse loss in the living mouse brain..  Molecular neurodegeneration.  12:-. 2017
• Pathogenic PS1 phosphorylation at Ser367..  eLife.  2017
• Topological analyses in APP/PS1 mice reveal that astrocytes do not migrate to amyloid-β plaques..  Proceedings of the National Academy of Sciences of the United States of America.  112:15556-61. 2015
• Neurofibrillary tangle-bearing neurons are functionally integrated in cortical circuits in vivo..  Proceedings of the National Academy of Sciences of the United States of America.  111:510-4. 2013
• Apolipoprotein E: isoform specific differences in tertiary structure and interaction with amyloid-β in human Alzheimer brain..  PloS one.  6:-. 2011
• Monitoring protein aggregation and toxicity in Alzheimer's disease mouse models using in vivo imaging..  Methods (San Diego, Calif.).  53:201-7. 2010
• Caspase activation precedes and leads to tangles..  Nature.  464:1201-4. 2010
• A reporter of local dendritic translocation shows plaque- related loss of neural system function in APP-transgenic mice..  The Journal of neuroscience : the official journal of the Society for Neuroscience.  29:12636-40. 2009
• Passive immunotherapy rapidly increases structural plasticity in a mouse model of Alzheimer disease..  Neurobiology of disease.  33:213-20. 2008
• Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease..  Nature.  451:720-4. 2008
• In vivo imaging reveals dissociation between caspase activation and acute neuronal death in tangle-bearing neurons..  The Journal of neuroscience : the official journal of the Society for Neuroscience.  28:862-7. 2008
• Monitoring tau-tubulin interactions utilizing second harmonic generation in living neurons..  Journal of biomedical optics.  13:-. 2008
• Impaired spine stability underlies plaque-related spine loss in an Alzheimer's disease mouse model..  The American journal of pathology.  171:1304-11. 2007
• Age-dependent cerebrovascular dysfunction in a transgenic mouse model of cerebral amyloid angiopathy..  Brain : a journal of neurology.  130:2310-9. 2007
• Physical and functional connection between auxilin and dynamin during endocytosis..  The EMBO journal.  25:4163-74. 2006
• Time-domain fluorescent plate reader for cell based protein-protein interaction and protein conformation assays..  Journal of biomedical optics.  11:-. 2006
• Dendritic spine abnormalities in amyloid precursor protein transgenic mice demonstrated by gene transfer and intravital multiphoton microscopy..  The Journal of neuroscience : the official journal of the Society for Neuroscience.  25:7278-87. 2005
• The low density lipoprotein receptor-related protein (LRP) is a novel beta-secretase (BACE1) substrate..  The Journal of biological chemistry.  280:17777-85. 2005
• Amyotrophic lateral sclerosis-associated SOD1 mutant proteins bind and aggregate with Bcl-2 in spinal cord mitochondria..  Neuron.  43:19-30. 2004
• Monitoring proteins in intact cells..  Science of aging knowledge environment : SAGE KE.  2003:-. 2003
• Amyloid precursor protein associates with a nicastrin-dependent docking site on the presenilin 1-gamma-secretase complex in cells demonstrated by fluorescence lifetime imaging..  The Journal of neuroscience : the official journal of the Society for Neuroscience.  23:4560-6. 2003