selected publications
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academic article
- Lewy body dementia: Overcoming barriers and identifying solutions.. Alzheimer's & dementia : the journal of the Alzheimer's Association. 20:2298-2308. 2024
- Direct visualization of CHIP-mediated degradation of alpha-synuclein in vivo: implications for PD therapeutics.. PloS one. 9:-. 2014
- Direct detection of alpha synuclein oligomers in vivo.. Acta neuropathologica communications. -. 2013
- Distinct roles in vivo for the ubiquitin-proteasome system and the autophagy-lysosomal pathway in the degradation of α-synuclein.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 31:14508-20. 2011
- Ubiquitinylation of α-synuclein by carboxyl terminus Hsp70-interacting protein (CHIP) is regulated by Bcl-2-associated athanogene 5 (BAG5).. PloS one. 6:-. 2011
- Studying protein degradation pathways in vivo using a cranial window-based approach.. Methods (San Diego, Calif.). 53:194-200. 2010
- Heat-shock protein 70 modulates toxic extracellular α-synuclein oligomers and rescues trans-synaptic toxicity.. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 25:326-36. 2010
- In vivo imaging of alpha-synuclein in mouse cortex demonstrates stable expression and differential subcellular compartment mobility.. PloS one. 5:-. 2010
- Tyrosine and serine phosphorylation of alpha-synuclein have opposing effects on neurotoxicity and soluble oligomer formation.. The Journal of clinical investigation. 119:3257-65. 2009
- Alpha-synuclein S129 phosphorylation mutants do not alter nigrostriatal toxicity in a rat model of Parkinson disease.. Journal of neuropathology and experimental neurology. 68:515-24. 2009
- Comparison of transduction efficiency of recombinant AAV serotypes 1, 2, 5, and 8 in the rat nigrostriatal system.. Journal of neurochemistry. 109:838-45. 2009
- Formation of toxic oligomeric alpha-synuclein species in living cells.. PloS one. 3:-. 2008
- Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease.. Science (New York, N.Y.). 317:516-9. 2007
- Small heat shock proteins protect against alpha-synuclein-induced toxicity and aggregation.. Biochemical and biophysical research communications. 351:631-8. 2006
- Dendritic spine abnormalities in amyloid precursor protein transgenic mice demonstrated by gene transfer and intravital multiphoton microscopy.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 25:7278-87. 2005
- Hsp70 Reduces alpha-Synuclein Aggregation and Toxicity.. The Journal of biological chemistry. 279:25497-502. 2004