selected publications
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academic article
- A novel neuroimaging signature for ADRD risk stratification in the community.. Alzheimer's & dementia : the journal of the Alzheimer's Association. 20:1881-1893. 2023
- Apolipoprotein E. Stroke. 54:1227-1235. 2023
- Association of Early Adulthood Hypertension and Blood Pressure Change With Late-Life Neuroimaging Biomarkers.. JAMA network open. 6:-. 2023
- Toward a statistical validation of brain signatures as robust measures of behavioral substrates.. Human brain mapping. 44:3094-3111. 2023
- Plasma biomarkers predict cognitive trajectories in an ethnoracially and clinically diverse cohort: Mediation with hippocampal volume.. Alzheimer's & dementia (Amsterdam, Netherlands). 14:-. 2022
- Genomic Studies Across the Lifespan Point to Early Mechanisms Determining Subcortical Volumes.. Biological psychiatry. Cognitive neuroscience and neuroimaging. 7:616-628. 2021
- A robust brain signature region approach for episodic memory performance in older adults.. Brain : a journal of neurology. 144:1089-1102. 2021
- Comparison of Education and Episodic Memory as Modifiers of Brain Atrophy Effects on Cognitive Decline: Implications for Measuring Cognitive Reserve.. Journal of the International Neuropsychological Society : JINS. 27:401-411. 2021
- Association of vascular brain injury, neurodegeneration, amyloid, and cognitive trajectory.. Neurology. 95:e2622-e2634. 2020
- Genetic architecture of subcortical brain structures in 38,851 individuals.. Nature genetics. 51:1624-1636. 2019
- Dynamic change of cognitive reserve: associations with changes in brain, cognition, and diagnosis.. Neurobiology of aging. 95-104. 2019
- The role of education in a vascular pathway to episodic memory: brain maintenance or cognitive reserve?. Neurobiology of aging. 109-118. 2019
- White Matter Hyperintensities and Hippocampal Atrophy in Relation to Cognition: The 90+ Study.. Journal of the American Geriatrics Society. 67:1827-1834. 2019
- Cerebral white matter free water: A sensitive biomarker of cognition and function.. Neurology. 92:e2221-e2231. 2019
- Vascular Burden Score Impacts Cognition Independent of Amyloid PET and MRI Measures of Alzheimer's Disease and Vascular Brain Injury.. Journal of Alzheimer's disease : JAD. 68:187-196. 2019
- "Liquid Biopsy" of White Matter Hyperintensity in Functionally Normal Elders.. Frontiers in aging neuroscience. -. 2018
- Cerebral tract integrity relates to white matter hyperintensities, cortex volume, and cognition.. Neurobiology of aging. 14-22. 2018
- Education amplifies brain atrophy effect on cognitive decline: implications for cognitive reserve.. Neurobiology of aging. 142-150. 2018
- Aortic Stiffness, Increased White Matter Free Water, and Altered Microstructural Integrity: A Continuum of Injury.. Stroke. 48:1567-1573. 2017
- Early Brain Loss in Circuits Affected by Alzheimer's Disease is Predicted by Fornix Microstructure but may be Independent of Gray Matter.. Frontiers in aging neuroscience. -. 2014
- White matter hyperintensities and their penumbra lie along a continuum of injury in the aging brain.. Stroke. 45:1721-6. 2014
- Robust measurement of individual localized changes to the aging hippocampus.. Computer vision and image understanding : CVIU. 117:1128-1137. 2013
- Effects of systolic blood pressure on white-matter integrity in young adults in the Framingham Heart Study: a cross-sectional study.. The Lancet. Neurology. 11:1039-47. 2012
- Combining boundary-based methods with tensor-based morphometry in the measurement of longitudinal brain change.. IEEE transactions on medical imaging. 32:223-36. 2012
- Coevolution of white matter hyperintensities and cognition in the elderly.. Neurology. 79:442-8. 2012
- Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans.. Proceedings of the National Academy of Sciences of the United States of America. 109:3985-90. 2012
- Influence of functional connectivity and structural MRI measures on episodic memory.. Neurobiology of aging. 33:2612-20. 2012
- Adaptive image segmentation for robust measurement of longitudinal brain tissue change.. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 5319-22. 2012
- White matter hyperintensity penumbra.. Stroke. 42:1917-22. 2011
- Longitudinal changes in white matter disease and cognition in the first year of the Alzheimer disease neuroimaging initiative.. Archives of neurology. 67:1370-8. 2010
- Vascular and degenerative processes differentially affect regional interhemispheric connections in normal aging, mild cognitive impairment, and Alzheimer disease.. Stroke. 41:1791-7. 2010
- Current concepts of analysis of cerebral white matter hyperintensities on magnetic resonance imaging.. Topics in magnetic resonance imaging : TMRI. 16:399-407. 2005
- Anatomical mapping of white matter hyperintensities (WMH): exploring the relationships between periventricular WMH, deep WMH, and total WMH burden.. Stroke. 36:50-5. 2004