academic article

• X-chromosome-wide association study for Alzheimer's disease..  Molecular psychiatry.  2024
• Meta-analysis of genome-wide association studies identifies ancestry-specific associations underlying circulating total tau levels..  Communications biology.  5:-. 2022
• New insights into the genetic etiology of Alzheimer's disease and related dementias..  Nature genetics.  54:412-436. 2022
• Family history aggregation unit-based tests to detect rare genetic variant associations with application to the Framingham Heart Study..  American journal of human genetics.  109:738-749. 2022
• Large-scale sequencing studies expand the known genetic architecture of Alzheimer's disease..  Alzheimer's & dementia (Amsterdam, Netherlands).  13:-. 2021
• Exploiting family history in aggregation unit-based genetic association tests..  European journal of human genetics : EJHG.  30:1355-1362. 2021
• Common variants in Alzheimer's disease and risk stratification by polygenic risk scores..  Nature communications.  12:-. 2021
• Genetic architecture of subcortical brain structures in 38,851 individuals..  Nature genetics.  51:1624-1636. 2019
• Analysis of Whole-Exome Sequencing Data for Alzheimer Disease Stratified by APOE Genotype..  JAMA neurology.  76:1099-1108. 2019
• Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing..  Nature genetics.  51:1423-1424. 2019
• Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing..  Nature genetics.  51:414-430. 2019
• Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting..  Neurology.  92:e486-e503. 2019
• Rare genetic variation implicated in non-Hispanic white families with Alzheimer disease..  Neurology. Genetics.  4:-. 2018
• Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease..  Alzheimer's & dementia (Amsterdam, Netherlands).  595-598. 2018
• Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation..  Molecular psychiatry.  25:1859-1875. 2018
• Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging..  Stroke.  49:1812-1819. 2018
• Quality control and integration of genotypes from two calling pipelines for whole genome sequence data in the Alzheimer's disease sequencing project..  Genomics.  111:808-818. 2018
• Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes..  Nature genetics.  50:524-537. 2018
• Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project..  Dementia and geriatric cognitive disorders.  45:1-17. 2018
• Whole genome sequence analyses of brain imaging measures in the Framingham Study..  Neurology.  90:e188-e196. 2017
• Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease..  Nature genetics.  49:1373-1384. 2017
• Novel genetic loci associated with hippocampal volume..  Nature communications.  -. 2017
• Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease..  PLoS genetics.  12:-. 2016
• Novel genetic loci underlying human intracranial volume identified through genome-wide association..  Nature neuroscience.  19:1569-1582. 2016
• Evaluation of a Genetic Risk Score to Improve Risk Prediction for Alzheimer's Disease..  Journal of Alzheimer's disease : JAD.  53:921-32. 2016
• Six Novel Loci Associated with Circulating VEGF Levels Identified by a Meta-analysis of Genome-Wide Association Studies..  PLoS genetics.  12:-. 2016
• Evaluation of power of the Illumina HumanOmni5M-4v1 BeadChip to detect risk variants for human complex diseases..  European journal of human genetics : EJHG.  24:1029-34. 2015
• Rare and Coding Region Genetic Variants Associated With Risk of Ischemic Stroke: The NHLBI Exome Sequence Project..  JAMA neurology.  72:781-8. 2015
• Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease..  Circulation.  131:2061-2069. 2015
• PLD3 variants in population studies..  Nature.  520:E2-3. 2015
• Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium..  Biological psychiatry.  77:749-63. 2014
• Mutation of FOXC1 and PITX2 induces cerebral small-vessel disease..  The Journal of clinical investigation.  124:4877-81. 2014
• Associations of NINJ2 sequence variants with incident ischemic stroke in the Cohorts for Heart and Aging in Genomic Epidemiology (CHARGE) consortium..  PloS one.  9:-. 2014
• Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2..  Arteriosclerosis, thrombosis, and vascular biology.  34:1093-101. 2014
• Multilocus genetic risk score associates with ischemic stroke in case-control and prospective cohort studies..  Stroke.  45:394-402. 2014
• Predicting stroke through genetic risk functions: the CHARGE Risk Score Project..  Stroke.  45:403-12. 2014
• Serum brain-derived neurotrophic factor and the risk for dementia: the Framingham Heart Study..  JAMA neurology.  71:55-61. 2014
• APOE genotype and MRI markers of cerebrovascular disease: systematic review and meta-analysis..  Neurology.  81:292-300. 2013
• Ischemic stroke is associated with the ABO locus: the EuroCLOT study..  Annals of neurology.  73:16-31. 2013
• Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies..  The Lancet. Neurology.  11:951-62. 2012
• Common variants at 12q14 and 12q24 are associated with hippocampal volume..  Nature genetics.  44:545-51. 2012
• Common variants at 6q22 and 17q21 are associated with intracranial volume..  Nature genetics.  44:539-44. 2012
• Identification of cis- and trans-acting genetic variants explaining up to half the variation in circulating vascular endothelial growth factor levels..  Circulation research.  109:554-63. 2011
• Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium..  Annals of neurology.  69:928-39. 2011
• Association of HSP70 and its co-chaperones with Alzheimer's disease..  Journal of Alzheimer's disease : JAD.  25:93-102. 2011
• Genetic correlates of brain aging on MRI and cognitive test measures: a genome-wide association and linkage analysis in the Framingham Study..  BMC medical genetics.  8 Suppl 1:-. 2007
• The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports..  BMC medical genetics.  8 Suppl 1:-. 2007
• Genome-wide scan for white matter hyperintensity: the Framingham Heart Study..  Stroke.  37:77-81. 2005