academic article

• Association of Plasma YKL-40 With MRI, CSF, and Cognitive Markers of Brain Health and Dementia.  Neurology.  2024
• Chromosome 10q24.32 Variants Associate with Brain Arterial Diameters in Diverse Populations: A Genome-Wide Association Study..  medRxiv : the preprint server for health sciences.  2023
• Epigenetic and integrative cross-omics analyses of cerebral white matter hyperintensities on MRI..  Brain : a journal of neurology.  146:492-506. 2023
• Association of Physical Inactivity with MRI Markers of Brain Aging: Assessing Mediation by Cardiometabolic and Epigenetic Factors..  Journal of Alzheimer's disease : JAD.  95:561-572. 2023
• Stroke genetics informs drug discovery and risk prediction across ancestries..  Nature.  611:115-123. 2022
• Association of Accelerometer-Measured Physical Activity and Sedentary Time with Epigenetic Markers of Aging..  Medicine and science in sports and exercise.  55:264-272. 2022
• Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning..  Molecular psychiatry.  27:4419-4431. 2022
• Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate..  Brain : a journal of neurology.  145:1992-2007. 2022
• New insights into the genetic etiology of Alzheimer's disease and related dementias..  Nature genetics.  54:412-436. 2022
• Correction: Association of low-frequency and rare coding variants with information processing speed..  Translational psychiatry.  12:-. 2022
• Associations Between Brainstem Volume and Alzheimer's Disease Pathology in Middle-Aged Individuals of the Framingham Heart Study..  Journal of Alzheimer's disease : JAD.  86:1603-1609. 2022
• Common variants in Alzheimer's disease and risk stratification by polygenic risk scores..  Nature communications.  12:-. 2021
• Exome Array Analysis of Early-Onset Ischemic Stroke..  Stroke.  51:3356-3360. 2020
• Corticosteroids and Regional Variations in Thickness of the Human Cerebral Cortex across the Lifespan..  Cerebral cortex (New York, N.Y. : 1991).  30:575-586. 2020
• Exome Array Analysis of Early-Onset Ischemic Stroke.  Stroke.  2020
• Genetic architecture of subcortical brain structures in 38,851 individuals..  Nature genetics.  51:1624-1636. 2019
• Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing..  Nature genetics.  51:1423-1424. 2019
• A genome-wide association study identifies genetic loci associated with specific lobar brain volumes..  Communications biology.  -. 2019
• The impact of APOE genotype on survival: Results of 38,537 participants from six population-based cohorts (E2-CHARGE)..  PloS one.  14:-. 2019
• Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function..  Nature communications.  10:-. 2019
• Association of variants in HTRA1 and NOTCH3 with MRI-defined extremes of cerebral small vessel disease in older subjects..  Brain : a journal of neurology.  142:1009-1023. 2019
• Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing..  Nature genetics.  51:414-430. 2019
• Abstract WP211: Exome Association Analysis of Small Vessel Young Onset Ischemic Stroke.  Stroke.  2019
• Methionine Sulfoxide Reductase-B3 Risk Allele Implicated in Alzheimer's Disease Associates with Increased Odds for Brain Infarcts..  Journal of Alzheimer's disease : JAD.  68:357-365. 2019
• Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume..  Nature communications.  9:-. 2018
• Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging..  Stroke.  49:1812-1819. 2018
• Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function..  Nature communications.  9:-. 2018
• Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes..  Nature genetics.  50:524-537. 2018
• Association of branched-chain amino acids and other circulating metabolites with risk of incident dementia and Alzheimer's disease: A prospective study in eight cohorts..  Alzheimer's & dementia : the journal of the Alzheimer's Association.  14:723-733. 2018
• Meta-analysis of epigenome-wide association studies of cognitive abilities..  Molecular psychiatry.  23:2133-2144. 2018
• Abstract WP160: Exome Array Analysis of Early-Onset Ischemic Stroke.  Stroke.  2018
• Whole blood gene expression and white matter Hyperintensities..  Molecular neurodegeneration.  12:-. 2017
• Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease..  Nature genetics.  49:1373-1384. 2017
• Whole exome sequence-based association analyses of plasma amyloid-β in African and European Americans; the Atherosclerosis Risk in Communities-Neurocognitive Study..  PloS one.  12:-. 2017
• Association of amine biomarkers with incident dementia and Alzheimer's disease in the Framingham Study..  Alzheimer's & dementia : the journal of the Alzheimer's Association.  13:1327-1336. 2017
• Abstract 56: An Exome Array Analysis of Ischemic Stroke in the Genetics of Early Onset Stroke Study.  Stroke.  2017
• White Matter Lesion Progression: Genome-Wide Search for Genetic Influences..  Stroke.  46:3048-57. 2015
• Circulating brain-derived neurotrophic factor concentrations and the risk of cardiovascular disease in the community..  Journal of the American Heart Association.  4:-. 2015
• Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI..  Circulation. Cardiovascular genetics.  8:398-409. 2015
• Genes from a translational analysis support a multifactorial nature of white matter hyperintensities..  Stroke.  46:341-7. 2015
• Lipid and lipoprotein measurements and the risk of ischemic vascular events: Framingham Study..  Neurology.  84:472-9. 2015
• Association of Alzheimer's disease GWAS loci with MRI markers of brain aging..  Neurobiology of aging.  36:1765.e7-1765.e16. 2015
• Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium..  Biological psychiatry.  77:749-63. 2014
• Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2..  Arteriosclerosis, thrombosis, and vascular biology.  34:1093-101. 2014
• Identification of cis- and trans-acting genetic variants explaining up to half the variation in circulating vascular endothelial growth factor levels..  Circulation research.  109:554-63. 2011
• Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium..  Annals of neurology.  69:928-39. 2011
• The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports..  BMC medical genetics.  8 Suppl 1:-. 2007