selected publications
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academic article
- Association of Plasma YKL-40 With MRI, CSF, and Cognitive Markers of Brain Health and Dementia. Neurology. 2024
- Chromosome 10q24.32 Variants Associate with Brain Arterial Diameters in Diverse Populations: A Genome-Wide Association Study.. medRxiv : the preprint server for health sciences. 2023
- Epigenetic and integrative cross-omics analyses of cerebral white matter hyperintensities on MRI.. Brain : a journal of neurology. 146:492-506. 2023
- Association of Physical Inactivity with MRI Markers of Brain Aging: Assessing Mediation by Cardiometabolic and Epigenetic Factors.. Journal of Alzheimer's disease : JAD. 95:561-572. 2023
- Stroke genetics informs drug discovery and risk prediction across ancestries.. Nature. 611:115-123. 2022
- Association of Accelerometer-Measured Physical Activity and Sedentary Time with Epigenetic Markers of Aging.. Medicine and science in sports and exercise. 55:264-272. 2022
- Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning.. Molecular psychiatry. 27:4419-4431. 2022
- Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate.. Brain : a journal of neurology. 145:1992-2007. 2022
- New insights into the genetic etiology of Alzheimer's disease and related dementias.. Nature genetics. 54:412-436. 2022
- Correction: Association of low-frequency and rare coding variants with information processing speed.. Translational psychiatry. 12:-. 2022
- Associations Between Brainstem Volume and Alzheimer's Disease Pathology in Middle-Aged Individuals of the Framingham Heart Study.. Journal of Alzheimer's disease : JAD. 86:1603-1609. 2022
- Common variants in Alzheimer's disease and risk stratification by polygenic risk scores.. Nature communications. 12:-. 2021
- Exome Array Analysis of Early-Onset Ischemic Stroke.. Stroke. 51:3356-3360. 2020
- Corticosteroids and Regional Variations in Thickness of the Human Cerebral Cortex across the Lifespan.. Cerebral cortex (New York, N.Y. : 1991). 30:575-586. 2020
- Exome Array Analysis of Early-Onset Ischemic Stroke. Stroke. 2020
- Genetic architecture of subcortical brain structures in 38,851 individuals.. Nature genetics. 51:1624-1636. 2019
- Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.. Nature genetics. 51:1423-1424. 2019
- A genome-wide association study identifies genetic loci associated with specific lobar brain volumes.. Communications biology. -. 2019
- The impact of APOE genotype on survival: Results of 38,537 participants from six population-based cohorts (E2-CHARGE).. PloS one. 14:-. 2019
- Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.. Nature communications. 10:-. 2019
- Association of variants in HTRA1 and NOTCH3 with MRI-defined extremes of cerebral small vessel disease in older subjects.. Brain : a journal of neurology. 142:1009-1023. 2019
- Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.. Nature genetics. 51:414-430. 2019
- Abstract WP211: Exome Association Analysis of Small Vessel Young Onset Ischemic Stroke. Stroke. 2019
- Methionine Sulfoxide Reductase-B3 Risk Allele Implicated in Alzheimer's Disease Associates with Increased Odds for Brain Infarcts.. Journal of Alzheimer's disease : JAD. 68:357-365. 2019
- Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume.. Nature communications. 9:-. 2018
- Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging.. Stroke. 49:1812-1819. 2018
- Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.. Nature communications. 9:-. 2018
- Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.. Nature genetics. 50:524-537. 2018
- Association of branched-chain amino acids and other circulating metabolites with risk of incident dementia and Alzheimer's disease: A prospective study in eight cohorts.. Alzheimer's & dementia : the journal of the Alzheimer's Association. 14:723-733. 2018
- Meta-analysis of epigenome-wide association studies of cognitive abilities.. Molecular psychiatry. 23:2133-2144. 2018
- Abstract WP160: Exome Array Analysis of Early-Onset Ischemic Stroke. Stroke. 2018
- Whole blood gene expression and white matter Hyperintensities.. Molecular neurodegeneration. 12:-. 2017
- Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.. Nature genetics. 49:1373-1384. 2017
- Whole exome sequence-based association analyses of plasma amyloid-β in African and European Americans; the Atherosclerosis Risk in Communities-Neurocognitive Study.. PloS one. 12:-. 2017
- Association of amine biomarkers with incident dementia and Alzheimer's disease in the Framingham Study.. Alzheimer's & dementia : the journal of the Alzheimer's Association. 13:1327-1336. 2017
- Abstract 56: An Exome Array Analysis of Ischemic Stroke in the Genetics of Early Onset Stroke Study. Stroke. 2017
- White Matter Lesion Progression: Genome-Wide Search for Genetic Influences.. Stroke. 46:3048-57. 2015
- Circulating brain-derived neurotrophic factor concentrations and the risk of cardiovascular disease in the community.. Journal of the American Heart Association. 4:-. 2015
- Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI.. Circulation. Cardiovascular genetics. 8:398-409. 2015
- Genes from a translational analysis support a multifactorial nature of white matter hyperintensities.. Stroke. 46:341-7. 2015
- Lipid and lipoprotein measurements and the risk of ischemic vascular events: Framingham Study.. Neurology. 84:472-9. 2015
- Association of Alzheimer's disease GWAS loci with MRI markers of brain aging.. Neurobiology of aging. 36:1765.e7-1765.e16. 2015
- Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium.. Biological psychiatry. 77:749-63. 2014
- Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2.. Arteriosclerosis, thrombosis, and vascular biology. 34:1093-101. 2014
- Identification of cis- and trans-acting genetic variants explaining up to half the variation in circulating vascular endothelial growth factor levels.. Circulation research. 109:554-63. 2011
- Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium.. Annals of neurology. 69:928-39. 2011
- The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports.. BMC medical genetics. 8 Suppl 1:-. 2007