academic article

• Tau impairs neural circuits, dominating amyloid-β effects, in Alzheimer models in vivo..  Nature Neuroscience.  22:57-64. 2018
• Tau reduction in the presence of amyloid-β prevents tau pathology and neuronal death in vivo..  Brain : a journal of neurology.  141:2194-2212. 2018
• Enhanced Tau Aggregation in the Presence of Amyloid β..  The American journal of pathology.  187:1601-1612. 2017
• Tau Antibody Targeting Pathological Species Blocks Neuronal Uptake and Interneuron Propagation of Tau in Vitro..  The American journal of pathology.  187:1399-1412. 2017
• Spread of tau down neural circuits precedes synapse and neuronal loss in the rTgTauEC mouse model of early Alzheimer's disease..  Synapse (New York, N.Y.).  71. 2017
• Human tau increases amyloid β plaque size but not amyloid β-mediated synapse loss in a novel mouse model of Alzheimer's disease..  The European journal of neuroscience.  44:3056-3066. 2016
• Seed-competent high-molecular-weight tau species accumulates in the cerebrospinal fluid of Alzheimer's disease mouse model and human patients..  Annals of neurology.  80:355-67. 2016
• Removing endogenous tau does not prevent tau propagation yet reduces its neurotoxicity..  The EMBO journal.  34:3028-41. 2015
• Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer's disease brain..  Nature communications.  -. 2015
• Tau-amyloid interactions in the rTgTauEC model of early Alzheimer's disease suggest amyloid-induced disruption of axonal projections and exacerbated axonal pathology..  The Journal of comparative neurology.  521:4236-48. 2013
• Soluble pathological tau in the entorhinal cortex leads to presynaptic deficits in an early Alzheimer's disease model..  Acta neuropathologica.  127:257-70. 2013
• Reversal of neurofibrillary tangles and tau-associated phenotype in the rTgTauEC model of early Alzheimer's disease..  The Journal of neuroscience : the official journal of the Society for Neuroscience.  33:13300-11. 2013
• Propagation of tau pathology in a model of early Alzheimer's disease..  Neuron.  73:685-97. 2012
• Tau accumulation causes mitochondrial distribution deficits in neurons in a mouse model of tauopathy and in human Alzheimer's disease brain..  The American journal of pathology.  179:2071-82. 2011
• Soluble tau species, not neurofibrillary aggregates, disrupt neural system integration in a tau transgenic model..  Journal of neuropathology and experimental neurology.  70:588-95. 2011
• Caspase activation precedes and leads to tangles..  Nature.  464:1201-4. 2010
• Tangle-bearing neurons survive despite disruption of membrane integrity in a mouse model of tauopathy..  Journal of neuropathology and experimental neurology.  68:757-61. 2009
• In vivo imaging reveals dissociation between caspase activation and acute neuronal death in tangle-bearing neurons..  The Journal of neuroscience : the official journal of the Society for Neuroscience.  28:862-7. 2008