selected publications
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academic article
- Neurofibrillary tangle-bearing neurons have reduced risk of cell death in mice with Alzheimer's pathology.. Cell reports. 43:-. 2024
- Reconstitution of the Alzheimer’s Disease Tau Core Structure from Recombinant Tau297–391 Yields Variable Quaternary Structures as Seen by Negative Stain and Cryo-EM. Biochemistry. 63:194-201. 2023
- Specific detection of tau seeding activity in Alzheimer's disease using rationally designed biosensor cells.. Molecular Neurodegeneration. 18:-. 2023
- An integrated genomic approach to dissect the genetic landscape regulating the cell-to-cell transfer of α-synuclein.. Cell reports. 35:-. 2021
- Conformational fingerprinting of tau variants and strains by Raman spectroscopy.. RSC advances. 11:8899-8915. 2021
- Conformational fingerprinting of tau variants and strains by Raman spectroscopy. RSC Advances. 2021
- Experimental evidence for the age dependence of tau protein spread in the brain.. Science advances. 5:-. 2019
- in vitro. The Journal of biological chemistry. 293:13247-13256. 2018
- Tau protein liquid-liquid phase separation can initiate tau aggregation.. The EMBO journal. 37. 2018
- Isoform- and cell type-specific structure of apolipoprotein E lipoparticles as revealed by a novel Forster resonance energy transfer assay.. The Journal of biological chemistry. 292:14720-14729. 2017
- Characterization of TauC3 antibody and demonstration of its potential to block tau propagation.. PloS one. 12:-. 2017
- Tailored transgene expression to specific cell types in the central nervous system after peripheral injection with AAV9.. Molecular therapy. Methods & clinical development. -. 2016
- Formation, release, and internalization of stable tau oligomers in cells.. Journal of neurochemistry. 139:1163-1174. 2016
- Seed-competent high-molecular-weight tau species accumulates in the cerebrospinal fluid of Alzheimer's disease mouse model and human patients.. Annals of neurology. 80:355-67. 2016
- Removing endogenous tau does not prevent tau propagation yet reduces its neurotoxicity.. The EMBO journal. 34:3028-41. 2015
- Direct visualization of CHIP-mediated degradation of alpha-synuclein in vivo: implications for PD therapeutics.. PloS one. 9:-. 2014
- Direct detection of alpha synuclein oligomers in vivo.. Acta neuropathologica communications. -. 2013
- Distinct roles in vivo for the ubiquitin-proteasome system and the autophagy-lysosomal pathway in the degradation of α-synuclein.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 31:14508-20. 2011
- Differential effect of three-repeat and four-repeat tau on mitochondrial axonal transport.. Journal of neurochemistry. 111:417-27. 2009
- Alpha-synuclein S129 phosphorylation mutants do not alter nigrostriatal toxicity in a rat model of Parkinson disease.. Journal of neuropathology and experimental neurology. 68:515-24. 2009