academic article

• Neurofibrillary tangle-bearing neurons have reduced risk of cell death in mice with Alzheimer's pathology..  Cell reports.  43:-. 2024
• Reconstitution of the Alzheimer’s Disease Tau Core Structure from Recombinant Tau297–391 Yields Variable Quaternary Structures as Seen by Negative Stain and Cryo-EM.  Biochemistry.  63:194-201. 2023
• Specific detection of tau seeding activity in Alzheimer's disease using rationally designed biosensor cells..  Molecular Neurodegeneration.  18:-. 2023
• An integrated genomic approach to dissect the genetic landscape regulating the cell-to-cell transfer of α-synuclein..  Cell reports.  35:-. 2021
• Conformational fingerprinting of tau variants and strains by Raman spectroscopy..  RSC advances.  11:8899-8915. 2021
• Conformational fingerprinting of tau variants and strains by Raman spectroscopy.  RSC Advances.  2021
• Experimental evidence for the age dependence of tau protein spread in the brain..  Science advances.  5:-. 2019
• in vitro.  The Journal of biological chemistry.  293:13247-13256. 2018
• Tau protein liquid-liquid phase separation can initiate tau aggregation..  The EMBO journal.  37. 2018
• Isoform- and cell type-specific structure of apolipoprotein E lipoparticles as revealed by a novel Forster resonance energy transfer assay..  The Journal of biological chemistry.  292:14720-14729. 2017
• Characterization of TauC3 antibody and demonstration of its potential to block tau propagation..  PloS one.  12:-. 2017
• Tailored transgene expression to specific cell types in the central nervous system after peripheral injection with AAV9..  Molecular therapy. Methods & clinical development.  -. 2016
• Formation, release, and internalization of stable tau oligomers in cells..  Journal of neurochemistry.  139:1163-1174. 2016
• Seed-competent high-molecular-weight tau species accumulates in the cerebrospinal fluid of Alzheimer's disease mouse model and human patients..  Annals of neurology.  80:355-67. 2016
• Removing endogenous tau does not prevent tau propagation yet reduces its neurotoxicity..  The EMBO journal.  34:3028-41. 2015
• Direct visualization of CHIP-mediated degradation of alpha-synuclein in vivo: implications for PD therapeutics..  PloS one.  9:-. 2014
• Direct detection of alpha synuclein oligomers in vivo..  Acta neuropathologica communications.  -. 2013
• Distinct roles in vivo for the ubiquitin-proteasome system and the autophagy-lysosomal pathway in the degradation of α-synuclein..  The Journal of neuroscience : the official journal of the Society for Neuroscience.  31:14508-20. 2011
• Differential effect of three-repeat and four-repeat tau on mitochondrial axonal transport..  Journal of neurochemistry.  111:417-27. 2009
• Alpha-synuclein S129 phosphorylation mutants do not alter nigrostriatal toxicity in a rat model of Parkinson disease..  Journal of neuropathology and experimental neurology.  68:515-24. 2009