selected publications
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academic article
- Association of Plasma YKL-40 With MRI, CSF, and Cognitive Markers of Brain Health and Dementia. Neurology. 2024
- Association between dietary inflammatory index score and incident dementia: results from the Framingham heart Study offspring cohort.. medRxiv : the preprint server for health sciences. 2023
- Cerebral small vessel disease burden is associated with decreased abundance of gut Barnesiella intestinihominis bacterium in the Framingham Heart Study.. Scientific reports. 13:-. 2023
- Secular Trends in Head Size and Cerebral Volumes In the Framingham Heart Study for Birth Years 1902-1985.. Research square. 2023
- Association of Red Blood Cell Omega-3 Fatty Acids With MRI Markers and Cognitive Function in Midlife: The Framingham Heart Study.. Neurology. 99:e2572-e2582. 2022
- Lighter sleep is associated with higher enlarged perivascular spaces burden in middle-aged and elderly individuals.. Sleep medicine. 558-564. 2022
- Self-reported sleepiness associates with greater brain and cortical volume and lower prevalence of ischemic covert brain infarcts in a community sample.. Sleep. 45. 2022
- A population-based meta-analysis of circulating GFAP for cognition and dementia risk.. Annals of clinical and translational neurology. 9:1574-1585. 2022
- Aging, prevalence and risk factors of MRI-visible enlarged perivascular spaces.. Aging. 14:6844-6858. 2022
- Higher Dietary Inflammatory Index scores are associated with brain MRI markers of brain aging: Results from the Framingham Heart Study Offspring cohort.. Alzheimer's & dementia : the journal of the Alzheimer's Association. 19:621-631. 2022
- Relations of Metabolic Health and Obesity to Brain Aging in Young to Middle-Aged Adults.. Journal of the American Heart Association. 11:-. 2022
- Insulin-Like Growth Factor, Inflammation, and MRI Markers of Alzheimer's Disease in Predominantly Middle-Aged Adults.. Journal of Alzheimer's disease : JAD. 88:311-322. 2022
- Systemic inflammation as a moderator between sleep and incident dementia.. Sleep. 44. 2021
- Incidence of Transient Ischemic Attack and Association With Long-term Risk of Stroke.. JAMA. 325:373-381. 2021
- Higher dietary inflammatory index scores are associated with increased incidence of all‐cause dementia in the Framingham Heart Study. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2021
- Interleukin-6 Interacts with Sleep Apnea Severity when Predicting Incident Alzheimer's Disease Dementia.. Journal of Alzheimer's Disease. 2021
- Interleukin-6 Interacts with Sleep Apnea Severity when Predicting Incident Alzheimer's Disease Dementia.. Journal of Alzheimer's disease : JAD. 79:1451-1457. 2021
- Assessment of Incidence and Risk Factors of Intracerebral Hemorrhage Among Participants in the Framingham Heart Study Between 1948 and 2016.. JAMA Neurology. 77:1252-1260. 2020
- Relation of plasma β-amyloid, clusterin, and tau with cerebral microbleeds: Framingham Heart Study.. Annals of clinical and translational neurology. 7:1083-1091. 2020
- The progression of carotid atherosclerosis and imaging markers of dementia.. Alzheimer's & dementia (New York, N. Y.). 6:-. 2020
- Plasma YKL40 as a biomarker for brain aging and injury in three community cohorts. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2020
- Association of CD14 with incident dementia and markers of brain aging and injury.. Neurology. 94:e254-e266. 2019
- Antihypertensive medications and risk for incident dementia and Alzheimer's disease: a meta-analysis of individual participant data from prospective cohort studies.. The Lancet. Neurology. 19:61-70. 2019
- Mid-life and late-life vascular risk factor burden and neuropathology in old age.. Annals of clinical and translational neurology. 6:2403-2412. 2019
- Genetic architecture of subcortical brain structures in 38,851 individuals.. Nature genetics. 51:1624-1636. 2019
- Accelerometer-determined physical activity and cognitive function in middle-aged and older adults from two generations of the Framingham Heart Study.. Alzheimer's & dementia (New York, N. Y.). 618-626. 2019
- Whole blood microRNA expression associated with stroke: Results from the Framingham Heart Study.. PloS one. 14:-. 2019
- Circulating IGFBP-2: a novel biomarker for incident dementia.. Annals of clinical and translational neurology. 6:1659-1670. 2019
- Plasma total-tau as a biomarker of stroke risk in the community.. Annals of neurology. 86:463-467. 2019
- Non-alcoholic fatty liver disease, liver fibrosis score and cognitive function in middle-aged adults: The Framingham Study.. Liver international : official journal of the International Association for the Study of the Liver. 39:1713-1721. 2019
- Temporal Trends in Ischemic Stroke Incidence in Younger Adults in the Framingham Study.. Stroke. 50:1558-1560. 2019
- Assessment of Plasma Total Tau Level as a Predictive Biomarker for Dementia and Related Endophenotypes.. JAMA neurology. 76:598-606. 2019
- Association of Accelerometer-Measured Light-Intensity Physical Activity With Brain Volume: The Framingham Heart Study.. JAMA network open. 2:-. 2019
- Circulating fibroblast growth factor 23 levels and incident dementia: The Framingham heart study.. PloS one. 14:-. 2019
- Association of metformin, sulfonylurea and insulin use with brain structure and function and risk of dementia and Alzheimer's disease: Pooled analysis from 5 cohorts.. PloS one. 14:-. 2019
- Self-Reported Physical Activity and Relations to Growth and Neurotrophic Factors in Diabetes Mellitus: The Framingham Offspring Study.. Journal of diabetes research. -. 2019
- Abstract TMP55: Abdominal Obesity Predicts Stroke Risk in the Framingham Study. Stroke. 2019
- Methionine Sulfoxide Reductase-B3 Risk Allele Implicated in Alzheimer's Disease Associates with Increased Odds for Brain Infarcts.. Journal of Alzheimer's disease : JAD. 68:357-365. 2019
- Circulating cortisol and cognitive and structural brain measures: The Framingham Heart Study.. Neurology. 91:e1961-e1970. 2018
- Vascular risk at younger ages most strongly associates with current and future brain volume.. Neurology. 91:e1479-e1486. 2018
- Circulating Vascular Growth Factors and Magnetic Resonance Imaging Markers of Small Vessel Disease and Atrophy in Middle-Aged Adults.. Stroke. 49:2227-2229. 2018
- DNA Methylation Signatures of Depressive Symptoms in Middle-aged and Elderly Persons: Meta-analysis of Multiethnic Epigenome-wide Studies.. JAMA psychiatry. 75:949-959. 2018
- Cerebral tract integrity relates to white matter hyperintensities, cortex volume, and cognition.. Neurobiology of aging. 14-22. 2018
- Author response: Sleep architecture and the risk of incident dementia in the community.. Neurology. 90:-. 2018
- Clinical significance of cerebral microbleeds on MRI: A comprehensive meta-analysis of risk of intracerebral hemorrhage, ischemic stroke, mortality, and dementia in cohort studies (v1).. International journal of stroke : official journal of the International Stroke Society. 13:454-468. 2018
- Abstract 171: Endothelial Microparticle Levels and Silent Stroke in the Framingham Heart Study. Stroke. 2018
- Abstract WMP49: Epidemiology of Transient Ischemic Attacks and Risk of Stroke in the Community-The Framingham Study. Stroke. 2018
- Vascular risk factor burden and new-onset depression in the community.. Preventive medicine. 348-350. 2017
- Atrial fibrillation and cognitive decline in the Framingham Heart Study.. Heart rhythm. 15:166-172. 2017
- Sleep architecture and the risk of incident dementia in the community.. Neurology. 89:1244-1250. 2017
- Inter-Relations of Orthostatic Blood Pressure Change, Aortic Stiffness, and Brain Structure and Function in Young Adults.. Journal of the American Heart Association. 6. 2017
- Response by Pase et al to Letter Regarding Article, "Sweetened Beverages and the Risks of Incident Stroke and Dementia".. Stroke. 48:-. 2017
- Response by Pase et al to Letters Regarding Article, "Sugar- and Artificially Sweetened Beverages and the Risks of Incident Stroke and Dementia. A Prospective Cohort Study".. Stroke. 2017
- Overweight, Obesity, and Survival After Stroke in the Framingham Heart Study.. Journal of the American Heart Association. 6. 2017
- Serum Insulin-Like Growth Factor 1 and the Risk of Ischemic Stroke: The Framingham Study.. Stroke. 48:1760-1765. 2017
- Aortic Stiffness, Increased White Matter Free Water, and Altered Microstructural Integrity: A Continuum of Injury.. Stroke. 48:1567-1573. 2017
- Sugar- and Artificially Sweetened Beverages and the Risks of Incident Stroke and Dementia: A Prospective Cohort Study.. Stroke. 48:1139-1146. 2017
- Associations between social relationship measures, serum brain-derived neurotrophic factor, and risk of stroke and dementia.. Alzheimer's & dementia (New York, N. Y.). 3:229-237. 2017
- Cerebral microbleeds and risk of incident dementia: the Framingham Heart Study.. Neurobiology of aging. 94-99. 2017
- Sugary beverage intake and preclinical Alzheimer's disease in the community.. Alzheimer's & dementia : the journal of the Alzheimer's Association. 13:955-964. 2017
- Prolonged sleep duration as a marker of early neurodegeneration predicting incident dementia.. Neurology. 88:1172-1179. 2017
- Revised Framingham Stroke Risk Profile to Reflect Temporal Trends.. Circulation. 135:1145-1159. 2017
- Cerebral Microbleeds as Predictors of Mortality: The Framingham Heart Study.. Stroke. 48:781-783. 2017
- Methionine Sulfoxide Reductase-B3 (MsrB3) Protein Associates with Synaptic Vesicles and its Expression Changes in the Hippocampi of Alzheimer's Disease Patients.. Journal of Alzheimer's disease : JAD. 60:43-56. 2017
- Overweight, Obesity, and Survival After Stroke in the Framingham Heart Study. Journal of the American Heart Association. 2017
- Revised Framingham Stroke Risk Profile to Reflect Temporal TrendsClinical Perspective. Circulation. 2017
- [O3–05–06]: REM SLEEP MECHANISMS PREDICT INCIDENT DEMENTIA IN THE FRAMINGHAM HEART STUDY. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2017
- Lacunar Infarcts and Intracerebral Hemorrhage Differences: A Nested Case-Control Analysis in the FHS (Framingham Heart Study).. Stroke. 48:486-489. 2016
- Serum brain-derived neurotrophic factor and risk of atrial fibrillation.. American heart journal. 69-73. 2016
- Aortic Stiffness and the Risk of Incident Mild Cognitive Impairment and Dementia.. Stroke. 47:2256-61. 2016
- Interaction Between Midlife Blood Glucose and APOE Genotype Predicts Later Alzheimer's Disease Pathology.. Journal of Alzheimer's disease : JAD. 53:1553-62. 2016
- Association of Ideal Cardiovascular Health With Vascular Brain Injury and Incident Dementia.. Stroke. 47:1201-6. 2016
- Factors Associated With New-Onset Depression After Stroke.. The Journal of neuropsychiatry and clinical neurosciences. 28:286-291. 2016
- Effects of Arterial Stiffness on Brain Integrity in Young Adults From the Framingham Heart Study.. Stroke. 47:1030-6. 2016
- Midlife exercise blood pressure, heart rate, and fitness relate to brain volume 2 decades later.. Neurology. 86:1313-1319. 2016
- Association of arterial stiffness with progression of subclinical brain and cognitive disease.. Neurology. 86:619-26. 2016
- Association of Aortic Stiffness With Cognition and Brain Aging in Young and Middle-Aged Adults: The Framingham Third Generation Cohort Study.. Hypertension (Dallas, Tex. : 1979). 67:513-9. 2016
- Association of Serum Vitamin D with the Risk of Incident Dementia and Subclinical Indices of Brain Aging: The Framingham Heart Study.. Journal of Alzheimer's disease : JAD. 51:451-61. 2016
- Differences Between Lacunar Infarcts and Deep Intracerebral hemorrhage: A Nested Case-Control Study from the Framingham Heart Study (S121). Annals of Neurology. 2016
- Serum Leptin Levels and the Risk of Stroke: The Framingham Study.. Stroke. 46:2881-5. 2015
- Diagnostic value of lobar microbleeds in individuals without intracerebral hemorrhage.. Alzheimer's & dementia : the journal of the Alzheimer's Association. 11:1480-1488. 2015
- Glucose indices are associated with cognitive and structural brain measures in young adults.. Neurology. 84:2329-37. 2015
- Low cardiac index is associated with incident dementia and Alzheimer disease: the Framingham Heart Study.. Circulation. 131:1333-9. 2015
- Lipid and lipoprotein measurements and the risk of ischemic vascular events: Framingham Study.. Neurology. 84:472-9. 2015
- Midlife Hypertension Risk and Cognition in the Non-Demented Oldest Old: Framingham Heart Study.. Journal of Alzheimer's disease : JAD. 47:197-204. 2015
- Normative Data for the Cognitively Intact Oldest-Old: The Framingham Heart Study.. Experimental aging research. 41:386-409. 2015
- Association between neuropathology and brain volume in the Framingham Heart Study.. Alzheimer disease and associated disorders. 28:219-25. 2014
- The Framingham Heart Study clock drawing performance: normative data from the offspring cohort.. Experimental aging research. 39:80-108. 2013
- Effects of systolic blood pressure on white-matter integrity in young adults in the Framingham Heart Study: a cross-sectional study.. The Lancet. Neurology. 11:1039-47. 2012
- The Framingham Brain Donation Program: neuropathology along the cognitive continuum.. Current Alzheimer research. 9:673-86. 2012
- Multiple biomarkers and risk of clinical and subclinical vascular brain injury: the Framingham Offspring Study.. Circulation. 125:2100-7. 2012
- Relation of left ventricular ejection fraction to cognitive aging (from the Framingham Heart Study).. The American journal of cardiology. 108:1346-51. 2011
- Association of metabolic dysregulation with volumetric brain magnetic resonance imaging and cognitive markers of subclinical brain aging in middle-aged adults: the Framingham Offspring Study.. Diabetes care. 34:1766-70. 2011
- Cardiac index is associated with brain aging: the Framingham Heart Study.. Circulation. 122:690-7. 2010
- O2‐05‐02: IMPACT OF AGE ON THE ASSOCIATION BETWEEN VASCULAR RISK FACTOR BURDEN AND BRAIN VOLUME. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2006
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