Sildenafil promotes smooth muscle preservation and ameliorates fibrosis through modulation of extracellular matrix and tissue growth factor gene expression after bilateral cavernosal nerve resection in the rat.
Academic Article
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publication date
- January 26, 2011
has subject area
- Animals
- Disease Models, Animal
- Endothelium, Vascular
- Epidermal Growth Factor
- Epiregulin
- Extracellular Matrix
- Fibrosis
- Gene Expression
- Intercellular Signaling Peptides and Proteins
- Male
- Matrix Metalloproteinase 1
- Matrix Metalloproteinase 3
- Nerve Tissue
- Penis
- Phosphodiesterase 5 Inhibitors
- Piperazines
- Purines
- Rats
- Sildenafil Citrate
- Sulfones
- Transforming Growth Factor beta2
published in
- The journal of sexual medicine Journal