selected publications
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academic article
- Epigenetic and integrative cross-omics analyses of cerebral white matter hyperintensities on MRI.. Brain : a journal of neurology. 146:492-506. 2023
- Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning.. Molecular psychiatry. 27:4419-4431. 2022
- Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate.. Brain : a journal of neurology. 145:1992-2007. 2022
- New insights into the genetic etiology of Alzheimer's disease and related dementias.. Nature genetics. 54:412-436. 2022
- Correction: Association of low-frequency and rare coding variants with information processing speed.. Translational psychiatry. 12:-. 2022
- Common variants in Alzheimer's disease and risk stratification by polygenic risk scores.. Nature communications. 12:-. 2021
- Cerebral small vessel disease genomics and its implications across the lifespan.. Nature communications. 11:-. 2020
- Multi-Ancestry Genome-wide Association Study Accounting for Gene-Psychosocial Factor Interactions Identifies Novel Loci for Blood Pressure Traits.. HGG advances. 2. 2020
- Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci.. Molecular psychiatry. 26:2111-2125. 2020
- Genetic architecture of subcortical brain structures in 38,851 individuals.. Nature genetics. 51:1624-1636. 2019
- Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.. Nature genetics. 51:1423-1424. 2019
- A genome-wide association study identifies genetic loci associated with specific lobar brain volumes.. Communications biology. -. 2019
- Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.. Nature communications. 10:-. 2019
- Association of variants in HTRA1 and NOTCH3 with MRI-defined extremes of cerebral small vessel disease in older subjects.. Brain : a journal of neurology. 142:1009-1023. 2019
- Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.. Nature genetics. 51:414-430. 2019
- Association of metformin, sulfonylurea and insulin use with brain structure and function and risk of dementia and Alzheimer's disease: Pooled analysis from 5 cohorts.. PloS one. 14:-. 2019
- Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting.. Neurology. 92:e486-e503. 2019
- GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.. Nature communications. 9:-. 2018
- Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume.. Nature communications. 9:-. 2018
- Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation.. Molecular psychiatry. 25:1859-1875. 2018
- Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging.. Stroke. 49:1812-1819. 2018
- Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.. Nature communications. 9:-. 2018
- Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.. Nature genetics. 50:524-537. 2018
- Association of branched-chain amino acids and other circulating metabolites with risk of incident dementia and Alzheimer's disease: A prospective study in eight cohorts.. Alzheimer's & dementia : the journal of the Alzheimer's Association. 14:723-733. 2018
- Meta-analysis of epigenome-wide association studies of cognitive abilities.. Molecular psychiatry. 23:2133-2144. 2018
- Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.. Nature genetics. 49:1373-1384. 2017
- Novel genetic loci associated with hippocampal volume.. Nature communications. -. 2017
- Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease.. PLoS genetics. 12:-. 2016
- Novel genetic loci underlying human intracranial volume identified through genome-wide association.. Nature neuroscience. 19:1569-1582. 2016
- Rare Exome Sequence Variants in CLCN6 Reduce Blood Pressure Levels and Hypertension Risk.. Circulation. Cardiovascular genetics. 9:64-70. 2015
- White Matter Lesion Progression: Genome-Wide Search for Genetic Influences.. Stroke. 46:3048-57. 2015
- Directional dominance on stature and cognition in diverse human populations.. Nature. 523:459-462. 2015
- Shared genetic basis for migraine and ischemic stroke: A genome-wide analysis of common variants.. Neurology. 84:2132-45. 2015
- Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease.. Circulation. 131:2061-2069. 2015
- PLD3 variants in population studies.. Nature. 520:E2-3. 2015
- Genetic studies of body mass index yield new insights for obesity biology.. Nature. 518:197-206. 2015
- Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI.. Circulation. Cardiovascular genetics. 8:398-409. 2015
- Common genetic variants influence human subcortical brain structures.. Nature. 520:224-9. 2015
- Association of Alzheimer's disease GWAS loci with MRI markers of brain aging.. Neurobiology of aging. 36:1765.e7-1765.e16. 2015
- Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium.. Biological psychiatry. 77:749-63. 2014
- GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy.. The journals of gerontology. Series A, Biological sciences and medical sciences. 70:110-8. 2014
- Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.. Nature. 514:92-97. 2014
- Multilocus genetic risk score associates with ischemic stroke in case-control and prospective cohort studies.. Stroke. 45:394-402. 2014
- Predicting stroke through genetic risk functions: the CHARGE Risk Score Project.. Stroke. 45:403-12. 2014
- Common variants at 12q14 and 12q24 are associated with hippocampal volume.. Nature genetics. 44:545-51. 2012
- Common variants at 6q22 and 17q21 are associated with intracranial volume.. Nature genetics. 44:539-44. 2012
- Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium.. Annals of neurology. 69:928-39. 2011
- Association of HSP70 and its co-chaperones with Alzheimer's disease.. Journal of Alzheimer's disease : JAD. 25:93-102. 2011