academic article

• Epigenetic and integrative cross-omics analyses of cerebral white matter hyperintensities on MRI..  Brain : a journal of neurology.  146:492-506. 2023
• Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning..  Molecular psychiatry.  27:4419-4431. 2022
• Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate..  Brain : a journal of neurology.  145:1992-2007. 2022
• New insights into the genetic etiology of Alzheimer's disease and related dementias..  Nature genetics.  54:412-436. 2022
• Correction: Association of low-frequency and rare coding variants with information processing speed..  Translational psychiatry.  12:-. 2022
• Common variants in Alzheimer's disease and risk stratification by polygenic risk scores..  Nature communications.  12:-. 2021
• Cerebral small vessel disease genomics and its implications across the lifespan..  Nature communications.  11:-. 2020
• Multi-Ancestry Genome-wide Association Study Accounting for Gene-Psychosocial Factor Interactions Identifies Novel Loci for Blood Pressure Traits..  HGG advances.  2. 2020
• Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci..  Molecular psychiatry.  26:2111-2125. 2020
• Genetic architecture of subcortical brain structures in 38,851 individuals..  Nature genetics.  51:1624-1636. 2019
• Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing..  Nature genetics.  51:1423-1424. 2019
• A genome-wide association study identifies genetic loci associated with specific lobar brain volumes..  Communications biology.  -. 2019
• Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function..  Nature communications.  10:-. 2019
• Association of variants in HTRA1 and NOTCH3 with MRI-defined extremes of cerebral small vessel disease in older subjects..  Brain : a journal of neurology.  142:1009-1023. 2019
• Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing..  Nature genetics.  51:414-430. 2019
• Association of metformin, sulfonylurea and insulin use with brain structure and function and risk of dementia and Alzheimer's disease: Pooled analysis from 5 cohorts..  PloS one.  14:-. 2019
• Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting..  Neurology.  92:e486-e503. 2019
• GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes..  Nature communications.  9:-. 2018
• Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume..  Nature communications.  9:-. 2018
• Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation..  Molecular psychiatry.  25:1859-1875. 2018
• Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging..  Stroke.  49:1812-1819. 2018
• Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function..  Nature communications.  9:-. 2018
• Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes..  Nature genetics.  50:524-537. 2018
• Association of branched-chain amino acids and other circulating metabolites with risk of incident dementia and Alzheimer's disease: A prospective study in eight cohorts..  Alzheimer's & dementia : the journal of the Alzheimer's Association.  14:723-733. 2018
• Meta-analysis of epigenome-wide association studies of cognitive abilities..  Molecular psychiatry.  23:2133-2144. 2018
• Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease..  Nature genetics.  49:1373-1384. 2017
• Novel genetic loci associated with hippocampal volume..  Nature communications.  -. 2017
• Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease..  PLoS genetics.  12:-. 2016
• Novel genetic loci underlying human intracranial volume identified through genome-wide association..  Nature neuroscience.  19:1569-1582. 2016
• Rare Exome Sequence Variants in CLCN6 Reduce Blood Pressure Levels and Hypertension Risk..  Circulation. Cardiovascular genetics.  9:64-70. 2015
• White Matter Lesion Progression: Genome-Wide Search for Genetic Influences..  Stroke.  46:3048-57. 2015
• Directional dominance on stature and cognition in diverse human populations..  Nature.  523:459-462. 2015
• Shared genetic basis for migraine and ischemic stroke: A genome-wide analysis of common variants..  Neurology.  84:2132-45. 2015
• Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease..  Circulation.  131:2061-2069. 2015
• PLD3 variants in population studies..  Nature.  520:E2-3. 2015
• Genetic studies of body mass index yield new insights for obesity biology..  Nature.  518:197-206. 2015
• Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI..  Circulation. Cardiovascular genetics.  8:398-409. 2015
• Common genetic variants influence human subcortical brain structures..  Nature.  520:224-9. 2015
• Association of Alzheimer's disease GWAS loci with MRI markers of brain aging..  Neurobiology of aging.  36:1765.e7-1765.e16. 2015
• Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium..  Biological psychiatry.  77:749-63. 2014
• GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy..  The journals of gerontology. Series A, Biological sciences and medical sciences.  70:110-8. 2014
• Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche..  Nature.  514:92-97. 2014
• Multilocus genetic risk score associates with ischemic stroke in case-control and prospective cohort studies..  Stroke.  45:394-402. 2014
• Predicting stroke through genetic risk functions: the CHARGE Risk Score Project..  Stroke.  45:403-12. 2014
• Common variants at 12q14 and 12q24 are associated with hippocampal volume..  Nature genetics.  44:545-51. 2012
• Common variants at 6q22 and 17q21 are associated with intracranial volume..  Nature genetics.  44:539-44. 2012
• Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium..  Annals of neurology.  69:928-39. 2011
• Association of HSP70 and its co-chaperones with Alzheimer's disease..  Journal of Alzheimer's disease : JAD.  25:93-102. 2011