selected publications
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academic article
- Neurocognitive profiles are associated with subsequent brain integrity in a sample of Hispanics/Latinos: Findings from the SOL-INCA-MRI study (HCHS/SOL).. Alzheimer's & dementia (Amsterdam, Netherlands). 16:-. 2024
- Hypertension Trends and White Matter Brain Injury in the Offspring Framingham Heart Study Cohort.. Hypertension. 81:87-95. 2023
- Relation of MRI-Visible Perivascular Spaces and Other MRI Markers of Cerebral Small Vessel Disease.. Brain sciences. 13. 2023
- Association of Early Adulthood Hypertension and Blood Pressure Change With Late-Life Neuroimaging Biomarkers.. JAMA network open. 6:-. 2023
- Placental growth factor as a sensitive biomarker for vascular cognitive impairment.. Alzheimer's & dementia : the journal of the Alzheimer's Association. 19:3519-3527. 2023
- Secular Trends in Head Size and Cerebral Volumes In the Framingham Heart Study for Birth Years 1902-1985.. Research square. 2023
- Association of Physical Inactivity with MRI Markers of Brain Aging: Assessing Mediation by Cardiometabolic and Epigenetic Factors.. Journal of Alzheimer's disease : JAD. 95:561-572. 2023
- MRI free water as a biomarker for cognitive performance: Validation in the MarkVCID consortium.. Alzheimer's & dementia (Amsterdam, Netherlands). 14:-. 2022
- Association of Red Blood Cell Omega-3 Fatty Acids With MRI Markers and Cognitive Function in Midlife: The Framingham Heart Study.. Neurology. 99:e2572-e2582. 2022
- Relations of postural change in blood pressure with hypertension-mediated organ damage in middle-aged adults of the Framingham heart study: A cross-sectional study.. Frontiers in cardiovascular medicine. -. 2022
- Multi-compartment diffusion magnetic resonance imaging models link tract-related characteristics with working memory performance in healthy older adults.. Frontiers in aging neuroscience. -. 2022
- Plasma biomarkers predict cognitive trajectories in an ethnoracially and clinically diverse cohort: Mediation with hippocampal volume.. Alzheimer's & dementia (Amsterdam, Netherlands). 14:-. 2022
- Instrumental validation of free water, peak-width of skeletonized mean diffusivity, and white matter hyperintensities: MarkVCID neuroimaging kits.. Alzheimer's & dementia (Amsterdam, Netherlands). 14:-. 2022
- Relations of Metabolic Health and Obesity to Brain Aging in Young to Middle-Aged Adults.. Journal of the American Heart Association. 11:-. 2022
- Coronary Artery Calcium Assessed Years Before Was Positively Associated With Subtle White Matter Injury of the Brain in Asymptomatic Middle-Aged Men: The Framingham Heart Study.. Circulation. Cardiovascular imaging. 14:-. 2021
- Digital sleep measures and white matter health in the Framingham Heart Study.. Exploration of medicine. 2:253-267. 2021
- MarkVCID cerebral small vessel consortium: II. Neuroimaging protocols.. Alzheimer's & dementia : the journal of the Alzheimer's Association. 17:716-725. 2021
- Association of vascular brain injury, neurodegeneration, amyloid, and cognitive trajectory.. Neurology. 95:e2622-e2634. 2020
- An IL-18-centered inflammatory network as a biomarker for cerebral white matter injury.. PloS one. 15:-. 2020
- Plasma YKL40 as a biomarker for brain aging and injury in three community cohorts. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2020
- Genetic architecture of subcortical brain structures in 38,851 individuals.. Nature genetics. 51:1624-1636. 2019
- A genome-wide association study identifies genetic loci associated with specific lobar brain volumes.. Communications biology. -. 2019
- Plasma total-tau as a biomarker of stroke risk in the community.. Annals of neurology. 86:463-467. 2019
- White Matter Hyperintensities and Hippocampal Atrophy in Relation to Cognition: The 90+ Study.. Journal of the American Geriatrics Society. 67:1827-1834. 2019
- Association of Accelerometer-Measured Light-Intensity Physical Activity With Brain Volume: The Framingham Heart Study.. JAMA network open. 2:-. 2019
- Cerebral white matter free water: A sensitive biomarker of cognition and function.. Neurology. 92:e2221-e2231. 2019
- Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting.. Neurology. 92:e486-e503. 2019
- Vascular Burden Score Impacts Cognition Independent of Amyloid PET and MRI Measures of Alzheimer's Disease and Vascular Brain Injury.. Journal of Alzheimer's disease : JAD. 68:187-196. 2019
- Circulating cortisol and cognitive and structural brain measures: The Framingham Heart Study.. Neurology. 91:e1961-e1970. 2018
- Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume.. Nature communications. 9:-. 2018
- Circulating Vascular Growth Factors and Magnetic Resonance Imaging Markers of Small Vessel Disease and Atrophy in Middle-Aged Adults.. Stroke. 49:2227-2229. 2018
- Cerebral tract integrity relates to white matter hyperintensities, cortex volume, and cognition.. Neurobiology of aging. 14-22. 2018
- Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging.. Stroke. 49:1812-1819. 2018
- Aortic Stiffness, Increased White Matter Free Water, and Altered Microstructural Integrity: A Continuum of Injury.. Stroke. 48:1567-1573. 2017
- Cerebral amyloid is associated with greater white-matter hyperintensity accrual in cognitively normal older adults.. Neurobiology of aging. 48-52. 2016
- Effects of Arterial Stiffness on Brain Integrity in Young Adults From the Framingham Heart Study.. Stroke. 47:1030-6. 2016
- Association of Aortic Stiffness With Cognition and Brain Aging in Young and Middle-Aged Adults: The Framingham Third Generation Cohort Study.. Hypertension (Dallas, Tex. : 1979). 67:513-9. 2016
- Glucose indices are associated with cognitive and structural brain measures in young adults.. Neurology. 84:2329-37. 2015
- Cooccurrence of vascular risk factors and late-life white-matter integrity changes.. Neurobiology of aging. 36:1670-1677. 2015
- White matter hyperintensities and their penumbra lie along a continuum of injury in the aging brain.. Stroke. 45:1721-6. 2014
- Effects of systolic blood pressure on white-matter integrity in young adults in the Framingham Heart Study: a cross-sectional study.. The Lancet. Neurology. 11:1039-47. 2012
- Coevolution of white matter hyperintensities and cognition in the elderly.. Neurology. 79:442-8. 2012
- White matter hyperintensity penumbra.. Stroke. 42:1917-22. 2011
- Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium.. Annals of neurology. 69:928-39. 2011