selected publications
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academic article
- Association of Plasma YKL-40 With MRI, CSF, and Cognitive Markers of Brain Health and Dementia. Neurology. 2024
- Genome-wide study investigating effector genes and polygenic prediction for kidney function in persons with ancestry from Africa and the Americas.. Cell genomics. 4:-. 2023
- Association of Mitochondrial DNA Copy Number With Brain MRI Markers and Cognitive Function: A Meta-analysis of Community-Based Cohorts.. Neurology. 100:e1930-e1943. 2023
- Chromosome 10q24.32 Variants Associate with Brain Arterial Diameters in Diverse Populations: A Genome-Wide Association Study.. medRxiv : the preprint server for health sciences. 2023
- Epigenetic and integrative cross-omics analyses of cerebral white matter hyperintensities on MRI.. Brain : a journal of neurology. 146:492-506. 2023
- Alzheimer's Disease Genetic Risk, Cognition, and Brain Aging in Midlife.. Annals of neurology. 93:629-634. 2022
- MRI free water as a biomarker for cognitive performance: Validation in the MarkVCID consortium.. Alzheimer's & dementia (Amsterdam, Netherlands). 14:-. 2022
- Genetic associations between sleep traits and cognitive ageing outcomes in the Hispanic Community Health Study/Study of Latinos.. EBioMedicine. -. 2022
- Stroke genetics informs drug discovery and risk prediction across ancestries.. Nature. 611:115-123. 2022
- A population-based meta-analysis of circulating GFAP for cognition and dementia risk.. Annals of clinical and translational neurology. 9:1574-1585. 2022
- Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning.. Molecular psychiatry. 27:4419-4431. 2022
- Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate.. Brain : a journal of neurology. 145:1992-2007. 2022
- Insights From a Large-Scale Whole-Genome Sequencing Study of Systolic Blood Pressure, Diastolic Blood Pressure, and Hypertension.. Hypertension (Dallas, Tex. : 1979). 79:1656-1667. 2022
- Meta-analysis of genome-wide association studies identifies ancestry-specific associations underlying circulating total tau levels.. Communications biology. 5:-. 2022
- New insights into the genetic etiology of Alzheimer's disease and related dementias.. Nature genetics. 54:412-436. 2022
- Correction: Association of low-frequency and rare coding variants with information processing speed.. Translational psychiatry. 12:-. 2022
- Blood DNA Methylation and Incident Coronary Heart Disease: Evidence From the Strong Heart Study.. JAMA cardiology. 6:1237-1246. 2021
- Common variants in Alzheimer's disease and risk stratification by polygenic risk scores.. Nature communications. 12:-. 2021
- MarkVCID cerebral small vessel consortium: I. Enrollment, clinical, fluid protocols.. Alzheimer's & dementia : the journal of the Alzheimer's Association. 17:704-715. 2021
- Cerebral small vessel disease genomics and its implications across the lifespan.. Nature communications. 11:-. 2020
- APOE alleles' association with cognitive function differs across Hispanic/Latino groups and genetic ancestry in the study of Latinos-investigation of neurocognitive aging (HCHS/SOL).. Alzheimer's & dementia : the journal of the Alzheimer's Association. 17:466-474. 2020
- Multi-Ancestry Genome-wide Association Study Accounting for Gene-Psychosocial Factor Interactions Identifies Novel Loci for Blood Pressure Traits.. HGG advances. 2. 2020
- Genome-Wide Association Study Meta-Analysis of Stroke in 22 000 Individuals of African Descent Identifies Novel Associations With Stroke.. Stroke. 51:2454-2463. 2020
- Twenty-seven-year time trends in dementia incidence in Europe and the United States: The Alzheimer Cohorts Consortium.. Neurology. 95:e519-e531. 2020
- Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci.. Molecular psychiatry. 26:2111-2125. 2020
- Epigenetic Age Acceleration and Cognitive Function in African American Adults in Midlife: The Atherosclerosis Risk in Communities Study.. The journals of gerontology. Series A, Biological sciences and medical sciences. 75:473-480. 2020
- Plasma YKL40 as a biomarker for brain aging and injury in three community cohorts. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2020
- Association of CD14 with incident dementia and markers of brain aging and injury.. Neurology. 94:e254-e266. 2019
- Genetic architecture of subcortical brain structures in 38,851 individuals.. Nature genetics. 51:1624-1636. 2019
- Circulating Monocyte Chemoattractant Protein-1 and Risk of Stroke: Meta-Analysis of Population-Based Studies Involving 17 180 Individuals.. Circulation research. 125:773-782. 2019
- Analysis of Whole-Exome Sequencing Data for Alzheimer Disease Stratified by APOE Genotype.. JAMA neurology. 76:1099-1108. 2019
- Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.. Nature genetics. 51:1423-1424. 2019
- Blood Leukocyte DNA Methylation Predicts Risk of Future Myocardial Infarction and Coronary Heart Disease.. Circulation. 140:645-657. 2019
- Association of variants in HTRA1 and NOTCH3 with MRI-defined extremes of cerebral small vessel disease in older subjects.. Brain : a journal of neurology. 142:1009-1023. 2019
- Omega-3 Fatty Acids and Genome-Wide Interaction Analyses Reveal DPP10-Pulmonary Function Association.. American journal of respiratory and critical care medicine. 199:631-642. 2019
- Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.. Nature genetics. 51:414-430. 2019
- Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels.. Circulation. 139:620-635. 2019
- Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting.. Neurology. 92:e486-e503. 2019
- A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology.. Blood. 133:967-977. 2019
- Genetics of the thrombomodulin-endothelial cell protein C receptor system and the risk of early-onset ischemic stroke.. PloS one. 13:-. 2018
- Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.. American journal of human genetics. 103:691-706. 2018
- Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume.. Nature communications. 9:-. 2018
- DNA Methylation Signatures of Depressive Symptoms in Middle-aged and Elderly Persons: Meta-analysis of Multiethnic Epigenome-wide Studies.. JAMA psychiatry. 75:949-959. 2018
- Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation.. Molecular psychiatry. 25:1859-1875. 2018
- Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging.. Stroke. 49:1812-1819. 2018
- Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.. Nature genetics. 50:524-537. 2018
- Meta-analysis of epigenome-wide association studies of cognitive abilities.. Molecular psychiatry. 23:2133-2144. 2018
- Whole genome sequence analyses of brain imaging measures in the Framingham Study.. Neurology. 90:e188-e196. 2017
- Trends in the incidence of dementia: design and methods in the Alzheimer Cohorts Consortium.. European journal of epidemiology. 32:931-938. 2017
- Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.. Nature genetics. 49:1373-1384. 2017
- Whole exome sequence-based association analyses of plasma amyloid-β in African and European Americans; the Atherosclerosis Risk in Communities-Neurocognitive Study.. PloS one. 12:-. 2017
- Genetic variation at 16q24.2 is associated with small vessel stroke.. Annals of neurology. 81:383-394. 2017
- Novel genetic loci associated with hippocampal volume.. Nature communications. -. 2017
- Novel genetic loci underlying human intracranial volume identified through genome-wide association.. Nature neuroscience. 19:1569-1582. 2016
- Genome-Wide Association Analysis of Young-Onset Stroke Identifies a Locus on Chromosome 10q25 Near HABP2.. Stroke. 47:307-16. 2016
- White Matter Lesion Progression: Genome-Wide Search for Genetic Influences.. Stroke. 46:3048-57. 2015
- Rare and Coding Region Genetic Variants Associated With Risk of Ischemic Stroke: The NHLBI Exome Sequence Project.. JAMA neurology. 72:781-8. 2015
- Shared genetic basis for migraine and ischemic stroke: A genome-wide analysis of common variants.. Neurology. 84:2132-45. 2015
- Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI.. Circulation. Cardiovascular genetics. 8:398-409. 2015
- Genetic overlap between diagnostic subtypes of ischemic stroke.. Stroke. 46:615-9. 2015
- Genes from a translational analysis support a multifactorial nature of white matter hyperintensities.. Stroke. 46:341-7. 2015
- Association of Alzheimer's disease GWAS loci with MRI markers of brain aging.. Neurobiology of aging. 36:1765.e7-1765.e16. 2015
- Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium.. Biological psychiatry. 77:749-63. 2014
- Mutation of FOXC1 and PITX2 induces cerebral small-vessel disease.. The Journal of clinical investigation. 124:4877-81. 2014
- Genome-wide association study of L-arginine and dimethylarginines reveals novel metabolic pathway for symmetric dimethylarginine.. Circulation. Cardiovascular genetics. 7:864-72. 2014
- Meta-analysis in more than 17,900 cases of ischemic stroke reveals a novel association at 12q24.12.. Neurology. 83:678-85. 2014
- Associations of NINJ2 sequence variants with incident ischemic stroke in the Cohorts for Heart and Aging in Genomic Epidemiology (CHARGE) consortium.. PloS one. 9:-. 2014
- Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2.. Arteriosclerosis, thrombosis, and vascular biology. 34:1093-101. 2014
- Multilocus genetic risk score associates with ischemic stroke in case-control and prospective cohort studies.. Stroke. 45:394-402. 2014
- Predicting stroke through genetic risk functions: the CHARGE Risk Score Project.. Stroke. 45:403-12. 2014
- Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.. Circulation. Cardiovascular genetics. 6:171-83. 2013
- Ischemic stroke is associated with the ABO locus: the EuroCLOT study.. Annals of neurology. 73:16-31. 2013
- Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies.. The Lancet. Neurology. 11:951-62. 2012
- Common variants at 12q14 and 12q24 are associated with hippocampal volume.. Nature genetics. 44:545-51. 2012
- Common variants at 6q22 and 17q21 are associated with intracranial volume.. Nature genetics. 44:539-44. 2012
- No association of ALOX5AP polymorphisms with risk of MRI-defined brain infarcts.. Neurobiology of aging. 33:629.e1-3. 2011
- Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium.. Annals of neurology. 69:928-39. 2011
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