selected publications
-
academic article
- X-chromosome-wide association study for Alzheimer's disease.. Molecular psychiatry. 2024
- Stroke genetics informs drug discovery and risk prediction across ancestries.. Nature. 611:115-123. 2022
- Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate.. Brain : a journal of neurology. 145:1992-2007. 2022
- New insights into the genetic etiology of Alzheimer's disease and related dementias.. Nature genetics. 54:412-436. 2022
- Migraine, Stroke, and Cervical Arterial Dissection: Shared Genetics for a Triad of Brain Disorders With Vascular Involvement.. Neurology. Genetics. 8:-. 2022
- Common variants in Alzheimer's disease and risk stratification by polygenic risk scores.. Nature communications. 12:-. 2021
- Cerebral small vessel disease genomics and its implications across the lifespan.. Nature communications. 11:-. 2020
- Genetic architecture of subcortical brain structures in 38,851 individuals.. Nature genetics. 51:1624-1636. 2019
- A genome-wide association study identifies genetic loci associated with specific lobar brain volumes.. Communications biology. -. 2019
- Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer's disease.. PloS one. 14:-. 2019
- Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.. Nature communications. 10:-. 2019
- Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting.. Neurology. 92:e486-e503. 2019
- Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.. Nature genetics. 51:51-62. 2018
- GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.. Nature communications. 9:-. 2018
- Genetics of the thrombomodulin-endothelial cell protein C receptor system and the risk of early-onset ischemic stroke.. PloS one. 13:-. 2018
- Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation.. Molecular psychiatry. 25:1859-1875. 2018
- Analysis of shared heritability in common disorders of the brain.. Science (New York, N.Y.). 360. 2018
- Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.. Nature communications. 9:-. 2018
- Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.. Nature genetics. 50:524-537. 2018
- Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.. Nature genetics. 49:1373-1384. 2017
- Novel genetic loci associated with hippocampal volume.. Nature communications. -. 2017
- Novel genetic loci underlying human intracranial volume identified through genome-wide association.. Nature neuroscience. 19:1569-1582. 2016
- Evaluation of a Genetic Risk Score to Improve Risk Prediction for Alzheimer's Disease.. Journal of Alzheimer's disease : JAD. 53:921-32. 2016
- Low-frequency and common genetic variation in ischemic stroke: The METASTROKE collaboration.. Neurology. 86:1217-26. 2016
- Genome-Wide Association Analysis of Young-Onset Stroke Identifies a Locus on Chromosome 10q25 Near HABP2.. Stroke. 47:307-16. 2016
- White Matter Lesion Progression: Genome-Wide Search for Genetic Influences.. Stroke. 46:3048-57. 2015
- Genetic studies of body mass index yield new insights for obesity biology.. Nature. 518:197-206. 2015
- Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI.. Circulation. Cardiovascular genetics. 8:398-409. 2015
- Association of Alzheimer's disease GWAS loci with MRI markers of brain aging.. Neurobiology of aging. 36:1765.e7-1765.e16. 2015
- Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium.. Biological psychiatry. 77:749-63. 2014
- Ischemic stroke is associated with the ABO locus: the EuroCLOT study.. Annals of neurology. 73:16-31. 2013
- Common variants at 12q14 and 12q24 are associated with hippocampal volume.. Nature genetics. 44:545-51. 2012
- Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium.. Annals of neurology. 69:928-39. 2011