selected publications
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academic article
- Association of Plasma YKL-40 With MRI, CSF, and Cognitive Markers of Brain Health and Dementia. Neurology. 2024
- Stroke genetics informs drug discovery and risk prediction across ancestries.. Nature. 611:115-123. 2022
- A population-based meta-analysis of circulating GFAP for cognition and dementia risk.. Annals of clinical and translational neurology. 9:1574-1585. 2022
- Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning.. Molecular psychiatry. 27:4419-4431. 2022
- Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate.. Brain : a journal of neurology. 145:1992-2007. 2022
- New insights into the genetic etiology of Alzheimer's disease and related dementias.. Nature genetics. 54:412-436. 2022
- Correction: Association of low-frequency and rare coding variants with information processing speed.. Translational psychiatry. 12:-. 2022
- Associations of Pulmonary Function with MRI Brain Volumes: A Coordinated Multi-Study Analysis.. Journal of Alzheimer's disease : JAD. 90:1073-1083. 2022
- Cerebral small vessel disease genomics and its implications across the lifespan.. Nature communications. 11:-. 2020
- Multi-Ancestry Genome-wide Association Study Accounting for Gene-Psychosocial Factor Interactions Identifies Novel Loci for Blood Pressure Traits.. HGG advances. 2. 2020
- Twenty-seven-year time trends in dementia incidence in Europe and the United States: The Alzheimer Cohorts Consortium.. Neurology. 95:e519-e531. 2020
- Fatty acids in the de novo lipogenesis pathway and incidence of type 2 diabetes: A pooled analysis of prospective cohort studies.. PLoS medicine. 17:-. 2020
- Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci.. Molecular psychiatry. 26:2111-2125. 2020
- Plasma YKL40 as a biomarker for brain aging and injury in three community cohorts. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2020
- Genetic architecture of subcortical brain structures in 38,851 individuals.. Nature genetics. 51:1624-1636. 2019
- Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.. Nature genetics. 51:1423-1424. 2019
- A genome-wide association study identifies genetic loci associated with specific lobar brain volumes.. Communications biology. -. 2019
- The impact of APOE genotype on survival: Results of 38,537 participants from six population-based cohorts (E2-CHARGE).. PloS one. 14:-. 2019
- Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality.. Circulation. 139:2422-2436. 2019
- Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.. Nature communications. 10:-. 2019
- Associations of circulating very-long-chain saturated fatty acids and incident type 2 diabetes: a pooled analysis of prospective cohort studies.. The American journal of clinical nutrition. 109:1216-1223. 2019
- Omega-3 Fatty Acids and Genome-Wide Interaction Analyses Reveal DPP10-Pulmonary Function Association.. American journal of respiratory and critical care medicine. 199:631-642. 2019
- Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.. Nature genetics. 51:414-430. 2019
- Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels.. Circulation. 139:620-635. 2019
- GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.. Nature communications. 9:-. 2018
- Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.. American journal of human genetics. 103:691-706. 2018
- Fatty acid biomarkers of dairy fat consumption and incidence of type 2 diabetes: A pooled analysis of prospective cohort studies.. PLoS medicine. 15:-. 2018
- Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume.. Nature communications. 9:-. 2018
- Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging.. Stroke. 49:1812-1819. 2018
- Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.. Nature communications. 9:-. 2018
- Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.. Nature genetics. 50:524-537. 2018
- Clinical significance of cerebral microbleeds on MRI: A comprehensive meta-analysis of risk of intracerebral hemorrhage, ischemic stroke, mortality, and dementia in cohort studies (v1).. International journal of stroke : official journal of the International Stroke Society. 13:454-468. 2018
- Trends in the incidence of dementia: design and methods in the Alzheimer Cohorts Consortium.. European journal of epidemiology. 32:931-938. 2017
- PCSK9. Circulation. Cardiovascular genetics. 10:-. 2017
- Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.. Nature genetics. 49:1373-1384. 2017
- Novel genetic loci associated with hippocampal volume.. Nature communications. -. 2017
- Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease.. PLoS genetics. 12:-. 2016
- Novel genetic loci underlying human intracranial volume identified through genome-wide association.. Nature neuroscience. 19:1569-1582. 2016
- Evaluation of a Genetic Risk Score to Improve Risk Prediction for Alzheimer's Disease.. Journal of Alzheimer's disease : JAD. 53:921-32. 2016
- Six Novel Loci Associated with Circulating VEGF Levels Identified by a Meta-analysis of Genome-Wide Association Studies.. PLoS genetics. 12:-. 2016
- White Matter Lesion Progression: Genome-Wide Search for Genetic Influences.. Stroke. 46:3048-57. 2015
- Directional dominance on stature and cognition in diverse human populations.. Nature. 523:459-462. 2015
- Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease.. Circulation. 131:2061-2069. 2015
- PLD3 variants in population studies.. Nature. 520:E2-3. 2015
- Genetic studies of body mass index yield new insights for obesity biology.. Nature. 518:197-206. 2015
- Common genetic variants influence human subcortical brain structures.. Nature. 520:224-9. 2015
- Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium.. Biological psychiatry. 77:749-63. 2014
- GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy.. The journals of gerontology. Series A, Biological sciences and medical sciences. 70:110-8. 2014
- Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.. Nature. 514:92-97. 2014
- Glycated hemoglobin measurement and prediction of cardiovascular disease.. JAMA. 311:1225-33. 2014
- Common variants at 12q14 and 12q24 are associated with hippocampal volume.. Nature genetics. 44:545-51. 2012
- Common variants at 6q22 and 17q21 are associated with intracranial volume.. Nature genetics. 44:539-44. 2012
- Identification of common variants associated with human hippocampal and intracranial volumes.. Nature genetics. 44:552-61. 2012
- A genome-wide association study of aging.. Neurobiology of aging. 32:2109.e15-28. 2011
- Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium.. Annals of neurology. 69:928-39. 2011