selected publications
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academic article
- Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate.. Brain : a journal of neurology. 145:1992-2007. 2022
- Genomic Studies Across the Lifespan Point to Early Mechanisms Determining Subcortical Volumes.. Biological psychiatry. Cognitive neuroscience and neuroimaging. 7:616-628. 2021
- Visit-to-Visit Blood Pressure Variability, Neuropathology, and Cognitive Decline.. Neurology. 96:e2812-e2823. 2021
- Cerebral small vessel disease genomics and its implications across the lifespan.. Nature communications. 11:-. 2020
- Antihypertensive medications and risk for incident dementia and Alzheimer's disease: a meta-analysis of individual participant data from prospective cohort studies.. The Lancet. Neurology. 19:61-70. 2019
- Genetic architecture of subcortical brain structures in 38,851 individuals.. Nature genetics. 51:1624-1636. 2019
- Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.. Nature communications. 10:-. 2019
- Association of variants in HTRA1 and NOTCH3 with MRI-defined extremes of cerebral small vessel disease in older subjects.. Brain : a journal of neurology. 142:1009-1023. 2019
- Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting.. Neurology. 92:e486-e503. 2019
- GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.. Nature communications. 9:-. 2018
- Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation.. Molecular psychiatry. 25:1859-1875. 2018
- Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.. Nature communications. 9:-. 2018
- Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.. Nature genetics. 50:524-537. 2018
- Trends in the incidence of dementia: design and methods in the Alzheimer Cohorts Consortium.. European journal of epidemiology. 32:931-938. 2017
- Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.. Nature genetics. 49:1373-1384. 2017
- Revised Framingham Stroke Risk Profile to Reflect Temporal Trends.. Circulation. 135:1145-1159. 2017
- Novel genetic loci associated with hippocampal volume.. Nature communications. -. 2017
- Revised Framingham Stroke Risk Profile to Reflect Temporal TrendsClinical Perspective. Circulation. 2017
- Novel genetic loci underlying human intracranial volume identified through genome-wide association.. Nature neuroscience. 19:1569-1582. 2016
- Reproducibility and variability of quantitative magnetic resonance imaging markers in cerebral small vessel disease.. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 36:1319-37. 2016
- White Matter Lesion Progression: Genome-Wide Search for Genetic Influences.. Stroke. 46:3048-57. 2015
- Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI.. Circulation. Cardiovascular genetics. 8:398-409. 2015
- Association of Alzheimer's disease GWAS loci with MRI markers of brain aging.. Neurobiology of aging. 36:1765.e7-1765.e16. 2015
- Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium.. Biological psychiatry. 77:749-63. 2014
- APOE genotype and MRI markers of cerebrovascular disease: systematic review and meta-analysis.. Neurology. 81:292-300. 2013
- Common variants at 12q14 and 12q24 are associated with hippocampal volume.. Nature genetics. 44:545-51. 2012
- Identification of common variants associated with human hippocampal and intracranial volumes.. Nature genetics. 44:552-61. 2012
- Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association/american stroke association.. Stroke. 42:2672-713. 2011
- Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium.. Annals of neurology. 69:928-39. 2011