selected publications
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academic article
- Association of Plasma YKL-40 With MRI, CSF, and Cognitive Markers of Brain Health and Dementia. Neurology. 2024
- Association of Mitochondrial DNA Copy Number With Brain MRI Markers and Cognitive Function: A Meta-analysis of Community-Based Cohorts.. Neurology. 100:e1930-e1943. 2023
- Epigenetic and integrative cross-omics analyses of cerebral white matter hyperintensities on MRI.. Brain : a journal of neurology. 146:492-506. 2023
- Alzheimer's Disease Genetic Risk, Cognition, and Brain Aging in Midlife.. Annals of neurology. 93:629-634. 2022
- Stroke genetics informs drug discovery and risk prediction across ancestries.. Nature. 611:115-123. 2022
- A population-based meta-analysis of circulating GFAP for cognition and dementia risk.. Annals of clinical and translational neurology. 9:1574-1585. 2022
- Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning.. Molecular psychiatry. 27:4419-4431. 2022
- Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate.. Brain : a journal of neurology. 145:1992-2007. 2022
- Meta-analysis of genome-wide association studies identifies ancestry-specific associations underlying circulating total tau levels.. Communications biology. 5:-. 2022
- New insights into the genetic etiology of Alzheimer's disease and related dementias.. Nature genetics. 54:412-436. 2022
- Correction: Association of low-frequency and rare coding variants with information processing speed.. Translational psychiatry. 12:-. 2022
- Mid-life epigenetic age, neuroimaging brain age, and cognitive function: coronary artery risk development in young adults (CARDIA) study.. Aging. 14:1691-1712. 2022
- Associations of Pulmonary Function with MRI Brain Volumes: A Coordinated Multi-Study Analysis.. Journal of Alzheimer's disease : JAD. 90:1073-1083. 2022
- Cerebral small vessel disease genomics and its implications across the lifespan.. Nature communications. 11:-. 2020
- Twenty-seven-year time trends in dementia incidence in Europe and the United States: The Alzheimer Cohorts Consortium.. Neurology. 95:e519-e531. 2020
- Plasma YKL40 as a biomarker for brain aging and injury in three community cohorts. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2020
- Antihypertensive medications and risk for incident dementia and Alzheimer's disease: a meta-analysis of individual participant data from prospective cohort studies.. The Lancet. Neurology. 19:61-70. 2019
- Genetic architecture of subcortical brain structures in 38,851 individuals.. Nature genetics. 51:1624-1636. 2019
- Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.. Nature genetics. 51:1423-1424. 2019
- A genome-wide association study identifies genetic loci associated with specific lobar brain volumes.. Communications biology. -. 2019
- The impact of APOE genotype on survival: Results of 38,537 participants from six population-based cohorts (E2-CHARGE).. PloS one. 14:-. 2019
- Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.. Nature communications. 10:-. 2019
- Association of variants in HTRA1 and NOTCH3 with MRI-defined extremes of cerebral small vessel disease in older subjects.. Brain : a journal of neurology. 142:1009-1023. 2019
- Omega-3 Fatty Acids and Genome-Wide Interaction Analyses Reveal DPP10-Pulmonary Function Association.. American journal of respiratory and critical care medicine. 199:631-642. 2019
- Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.. Nature genetics. 51:414-430. 2019
- Harmonizing brain magnetic resonance imaging methods for vascular contributions to neurodegeneration.. Alzheimer's & dementia (Amsterdam, Netherlands). 191-204. 2019
- Association of metformin, sulfonylurea and insulin use with brain structure and function and risk of dementia and Alzheimer's disease: Pooled analysis from 5 cohorts.. PloS one. 14:-. 2019
- Distribution of cerebral microbleeds in the East and West: Individual participant meta-analysis.. Neurology. 92:e1086-e1097. 2019
- Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels.. Circulation. 139:620-635. 2019
- Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting.. Neurology. 92:e486-e503. 2019
- GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.. Nature communications. 9:-. 2018
- Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume.. Nature communications. 9:-. 2018
- Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging.. Stroke. 49:1812-1819. 2018
- Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.. Nature communications. 9:-. 2018
- Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.. Nature genetics. 50:524-537. 2018
- Clinical significance of cerebral microbleeds on MRI: A comprehensive meta-analysis of risk of intracerebral hemorrhage, ischemic stroke, mortality, and dementia in cohort studies (v1).. International journal of stroke : official journal of the International Stroke Society. 13:454-468. 2018
- Trends in the incidence of dementia: design and methods in the Alzheimer Cohorts Consortium.. European journal of epidemiology. 32:931-938. 2017
- Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.. Nature genetics. 49:1373-1384. 2017
- Genetic variation at 16q24.2 is associated with small vessel stroke.. Annals of neurology. 81:383-394. 2017
- Novel genetic loci associated with hippocampal volume.. Nature communications. -. 2017
- Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease.. PLoS genetics. 12:-. 2016
- Impact of Hypertension on Cognitive Function: A Scientific Statement From the American Heart Association.. Hypertension (Dallas, Tex. : 1979). 68:e67-e94. 2016
- Novel genetic loci underlying human intracranial volume identified through genome-wide association.. Nature neuroscience. 19:1569-1582. 2016
- Evaluation of a Genetic Risk Score to Improve Risk Prediction for Alzheimer's Disease.. Journal of Alzheimer's disease : JAD. 53:921-32. 2016
- White Matter Lesion Progression: Genome-Wide Search for Genetic Influences.. Stroke. 46:3048-57. 2015
- Directional dominance on stature and cognition in diverse human populations.. Nature. 523:459-462. 2015
- Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease.. Circulation. 131:2061-2069. 2015
- PLD3 variants in population studies.. Nature. 520:E2-3. 2015
- Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI.. Circulation. Cardiovascular genetics. 8:398-409. 2015
- Common genetic variants influence human subcortical brain structures.. Nature. 520:224-9. 2015
- Genes from a translational analysis support a multifactorial nature of white matter hyperintensities.. Stroke. 46:341-7. 2015
- Association of Alzheimer's disease GWAS loci with MRI markers of brain aging.. Neurobiology of aging. 36:1765.e7-1765.e16. 2015
- Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium.. Biological psychiatry. 77:749-63. 2014
- Plasma amyloid-β and risk of Alzheimer's disease in the Framingham Heart Study.. Alzheimer's & dementia : the journal of the Alzheimer's Association. 11:249-57.e1. 2014
- GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy.. The journals of gerontology. Series A, Biological sciences and medical sciences. 70:110-8. 2014
- Multilocus genetic risk score associates with ischemic stroke in case-control and prospective cohort studies.. Stroke. 45:394-402. 2014
- Predicting stroke through genetic risk functions: the CHARGE Risk Score Project.. Stroke. 45:403-12. 2014
- Common variants at 12q14 and 12q24 are associated with hippocampal volume.. Nature genetics. 44:545-51. 2012
- Common variants at 6q22 and 17q21 are associated with intracranial volume.. Nature genetics. 44:539-44. 2012
- Identification of common variants associated with human hippocampal and intracranial volumes.. Nature genetics. 44:552-61. 2012
- No association of ALOX5AP polymorphisms with risk of MRI-defined brain infarcts.. Neurobiology of aging. 33:629.e1-3. 2011
- A genome-wide association study of aging.. Neurobiology of aging. 32:2109.e15-28. 2011
- Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association/american stroke association.. Stroke. 42:2672-713. 2011
- Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium.. Annals of neurology. 69:928-39. 2011
- Education and APOE-e4 in longitudinal cognitive decline: MacArthur Studies of Successful Aging.. The journals of gerontology. Series B, Psychological sciences and social sciences. 60:P74-83. 2005
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