selected publications
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academic article
- Pathways to personalized medicine-Embracing heterogeneity for progress in clinical therapeutics research in Alzheimer's disease.. Alzheimer's & dementia : the journal of the Alzheimer's Association. 20:7384-7394. 2024
- APOE. Neurology Genetics. 9:-. 2023
- Causal inference in medical records and complementary systems pharmacology for metformin drug repurposing towards dementia.. Nature communications. 13:-. 2022
- APOE. Nature Aging. 1:919-931. 2021
- Opposing Roles of apolipoprotein E in aging and neurodegeneration.. Life science alliance. 2. 2019
- Neuronal calcineurin transcriptional targets parallel changes observed in Alzheimer disease brain.. Journal of neurochemistry. 147:24-39. 2018
- Tau induces blood vessel abnormalities and angiogenesis-related gene expression in P301L transgenic mice and human Alzheimer's disease.. Proceedings of the National Academy of Sciences of the United States of America. 115:E1289-E1298. 2018
- APOE-related risk of mild cognitive impairment and dementia for prevention trials: An analysis of four cohorts.. PLoS medicine. 14:-. 2017
- Soluble oligomeric amyloid-β induces calcium dyshomeostasis that precedes synapse loss in the living mouse brain.. Molecular neurodegeneration. 12:-. 2017
- Thal Amyloid Stages Do Not Significantly Impact the Correlation Between Neuropathological Change and Cognition in the Alzheimer Disease Continuum.. Journal of neuropathology and experimental neurology. 75:516-26. 2016
- Maternal dementia age at onset in relation to amyloid burden in non-demented elderly offspring.. Neurobiology of aging. 61-67. 2015
- Tau positron emission tomographic imaging in aging and early Alzheimer disease.. Annals of neurology. 79:110-9. 2015
- Plaque-Associated Local Toxicity Increases over the Clinical Course of Alzheimer Disease.. The American journal of pathology. 186:375-84. 2015
- APOEε2 is associated with milder clinical and pathological Alzheimer disease.. Annals of neurology. 77:917-29. 2015
- The Influence of Vascular Risk Factors and Stroke on Cognition in Late Life: Analysis of the NACC Cohort.. Alzheimer disease and associated disorders. 29:287-93. 2015
- Tau pathology does not affect experience-driven single-neuron and network-wide Arc/Arg3.1 responses.. Acta neuropathologica communications. -. 2014
- Anti-ApoE antibody given after plaque onset decreases Aβ accumulation and improves brain function in a mouse model of Aβ amyloidosis.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 34:7281-92. 2014
- Mild to moderate Alzheimer dementia with insufficient neuropathological changes.. Annals of neurology. 75:597-601. 2014
- Gene transfer of human Apoe isoforms results in differential modulation of amyloid deposition and neurotoxicity in mouse brain.. Science translational medicine. 5:-. 2013
- Differential relationships of reactive astrocytes and microglia to fibrillar amyloid deposits in Alzheimer disease.. Journal of neuropathology and experimental neurology. 72:462-71. 2013
- Calcineurin activation causes retinal ganglion cell degeneration.. Molecular vision. 2828-38. 2012
- Orchestrated experience-driven Arc responses are disrupted in a mouse model of Alzheimer's disease.. Nature neuroscience. 15:1422-9. 2012
- The SIST-M: predictive validity of a brief structured clinical dementia rating interview.. Alzheimer disease and associated disorders. 26:225-31. 2012
- Calcineurin inhibition with systemic FK506 treatment increases dendritic branching and dendritic spine density in healthy adult mouse brain.. Neuroscience letters. 487:260-3. 2010