Expression of Wnt3 activates Wnt/β-catenin pathway and promotes EMT-like phenotype in trastuzumab-resistant HER2-overexpressing breast cancer cells.
Academic Article
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Overview
publication date
- October 15, 2012
has subject area
- Antibodies, Monoclonal, Humanized
- Breast Neoplasms
- Cadherins
- Cell Line, Tumor
- Drug Resistance, Neoplasm
- ErbB Receptors
- Female
- Humans
- Nuclear Proteins
- Organic Cation Transport Proteins
- Phenotype
- Receptor, ErbB-2
- Snail Family Transcription Factors
- Transcription Factors
- Transcriptional Activation
- Trastuzumab
- Twist-Related Protein 1
- Wnt Signaling Pathway
- Wnt3 Protein
- beta Catenin
published in
- Molecular cancer research : MCR Journal