selected publications
-
academic article
- Tau PTM Profiles Identify Patient Heterogeneity and Stages of Alzheimer's Disease.. Cell. 183:1699-1713.e13. 2020
- Secretion and Uptake of α-Synuclein Via Extracellular Vesicles in Cultured Cells.. Cellular and molecular neurobiology. 38:1539-1550. 2018
- CRISPR/Cas9 Mediated Disruption of the Swedish APP Allele as a Therapeutic Approach for Early-Onset Alzheimer's Disease.. Molecular therapy. Nucleic acids. 429-440. 2018
- Mutant torsinA in the heterozygous DYT1 state compromises HSV propagation in infected neurons and fibroblasts.. Scientific reports. 8:-. 2018
- Characterization of TauC3 antibody and demonstration of its potential to block tau propagation.. PloS one. 12:-. 2017
- Tau Antibody Targeting Pathological Species Blocks Neuronal Uptake and Interneuron Propagation of Tau in Vitro.. The American journal of pathology. 187:1399-1412. 2017
- Soluble oligomeric amyloid-β induces calcium dyshomeostasis that precedes synapse loss in the living mouse brain.. Molecular neurodegeneration. 12:-. 2017
- Dynamic presenilin 1 and synaptotagmin 1 interaction modulates exocytosis and amyloid β production.. Molecular neurodegeneration. 12:-. 2017
- Formation, release, and internalization of stable tau oligomers in cells.. Journal of neurochemistry. 139:1163-1174. 2016
- Seed-competent high-molecular-weight tau species accumulates in the cerebrospinal fluid of Alzheimer's disease mouse model and human patients.. Annals of neurology. 80:355-67. 2016
- Removing endogenous tau does not prevent tau propagation yet reduces its neurotoxicity.. The EMBO journal. 34:3028-41. 2015
- Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer's disease brain.. Nature communications. -. 2015
- Oxidative stress and lipid peroxidation are upstream of amyloid pathology.. Neurobiology of disease. 109-19. 2015
- A Food and Drug Administration-approved asthma therapeutic agent impacts amyloid β in the brain in a transgenic model of Alzheimer disease.. The Journal of biological chemistry. 290:1966-78. 2014
- Gene transfer of human Apoe isoforms results in differential modulation of amyloid deposition and neurotoxicity in mouse brain.. Science translational medicine. 5:-. 2013
- Brain interstitial oligomeric amyloid β increases with age and is resistant to clearance from brain in a mouse model of Alzheimer's disease.. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 27:3239-48. 2013