academic article

• VWA3A.  Molecular therapy. Nucleic acids.  296-304. 2023
• APOE4 derived from astrocytes leads to blood-brain barrier impairment..  Brain : a journal of neurology.  145:3582-3593. 2022
• APOE.  Nature Aging.  1:919-931. 2021
• Experimental evidence for the age dependence of tau protein spread in the brain..  Science advances.  5:-. 2019
• The Major Risk Factors for Alzheimer's Disease: Age, Sex, and Genes Modulate the Microglia Response to Aβ Plaques..  Cell reports.  27:1293-1306.e6. 2019
• Opposing Roles of apolipoprotein E in aging and neurodegeneration..  Life science alliance.  2. 2019
• Neuronal calcineurin transcriptional targets parallel changes observed in Alzheimer disease brain..  Journal of neurochemistry.  147:24-39. 2018
• Efficient Gene Transfer to the Central Nervous System by Single-Stranded Anc80L65..  Molecular therapy. Methods & clinical development.  197-209. 2018
• in vitro.  The Journal of biological chemistry.  293:13247-13256. 2018
• Virus vector-mediated genetic modification of brain tumor stromal cells after intravenous delivery..  Journal of neuro-oncology.  139:293-305. 2018
• Targeting of nonlipidated, aggregated apoE with antibodies inhibits amyloid accumulation..  The Journal of clinical investigation.  128:2144-2155. 2018
• Isoform- and cell type-specific structure of apolipoprotein E lipoparticles as revealed by a novel Forster resonance energy transfer assay..  The Journal of biological chemistry.  292:14720-14729. 2017
• Soluble oligomeric amyloid-β induces calcium dyshomeostasis that precedes synapse loss in the living mouse brain..  Molecular neurodegeneration.  12:-. 2017
• Trafficking of adeno-associated virus vectors across a model of the blood-brain barrier; a comparative study of transcytosis and transduction using primary human brain endothelial cells..  Journal of neurochemistry.  140:216-230. 2016
• Tailored transgene expression to specific cell types in the central nervous system after peripheral injection with AAV9..  Molecular therapy. Methods & clinical development.  -. 2016
• Topological analyses in APP/PS1 mice reveal that astrocytes do not migrate to amyloid-β plaques..  Proceedings of the National Academy of Sciences of the United States of America.  112:15556-61. 2015
• Massachusetts Alzheimer's Disease Research Center: progress and challenges..  Alzheimer's & dementia : the journal of the Alzheimer's Association.  11:1241-5. 2015
• A Food and Drug Administration-approved asthma therapeutic agent impacts amyloid β in the brain in a transgenic model of Alzheimer disease..  The Journal of biological chemistry.  290:1966-78. 2014
• Anti-ApoE antibody given after plaque onset decreases Aβ accumulation and improves brain function in a mouse model of Aβ amyloidosis..  The Journal of neuroscience : the official journal of the Society for Neuroscience.  34:7281-92. 2014
• RNA aptamer probes as optical imaging agents for the detection of amyloid plaques..  PloS one.  9:-. 2014
• Gene transfer of human Apoe isoforms results in differential modulation of amyloid deposition and neurotoxicity in mouse brain..  Science translational medicine.  5:-. 2013