selected publications
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academic article
- VWA3A. Molecular therapy. Nucleic acids. 296-304. 2023
- APOE4 derived from astrocytes leads to blood-brain barrier impairment.. Brain : a journal of neurology. 145:3582-3593. 2022
- APOE. Nature Aging. 1:919-931. 2021
- Experimental evidence for the age dependence of tau protein spread in the brain.. Science advances. 5:-. 2019
- The Major Risk Factors for Alzheimer's Disease: Age, Sex, and Genes Modulate the Microglia Response to Aβ Plaques.. Cell reports. 27:1293-1306.e6. 2019
- Opposing Roles of apolipoprotein E in aging and neurodegeneration.. Life science alliance. 2. 2019
- Neuronal calcineurin transcriptional targets parallel changes observed in Alzheimer disease brain.. Journal of neurochemistry. 147:24-39. 2018
- Efficient Gene Transfer to the Central Nervous System by Single-Stranded Anc80L65.. Molecular therapy. Methods & clinical development. 197-209. 2018
- in vitro. The Journal of biological chemistry. 293:13247-13256. 2018
- Virus vector-mediated genetic modification of brain tumor stromal cells after intravenous delivery.. Journal of neuro-oncology. 139:293-305. 2018
- Targeting of nonlipidated, aggregated apoE with antibodies inhibits amyloid accumulation.. The Journal of clinical investigation. 128:2144-2155. 2018
- Isoform- and cell type-specific structure of apolipoprotein E lipoparticles as revealed by a novel Forster resonance energy transfer assay.. The Journal of biological chemistry. 292:14720-14729. 2017
- Soluble oligomeric amyloid-β induces calcium dyshomeostasis that precedes synapse loss in the living mouse brain.. Molecular neurodegeneration. 12:-. 2017
- Trafficking of adeno-associated virus vectors across a model of the blood-brain barrier; a comparative study of transcytosis and transduction using primary human brain endothelial cells.. Journal of neurochemistry. 140:216-230. 2016
- Tailored transgene expression to specific cell types in the central nervous system after peripheral injection with AAV9.. Molecular therapy. Methods & clinical development. -. 2016
- Topological analyses in APP/PS1 mice reveal that astrocytes do not migrate to amyloid-β plaques.. Proceedings of the National Academy of Sciences of the United States of America. 112:15556-61. 2015
- Massachusetts Alzheimer's Disease Research Center: progress and challenges.. Alzheimer's & dementia : the journal of the Alzheimer's Association. 11:1241-5. 2015
- A Food and Drug Administration-approved asthma therapeutic agent impacts amyloid β in the brain in a transgenic model of Alzheimer disease.. The Journal of biological chemistry. 290:1966-78. 2014
- Anti-ApoE antibody given after plaque onset decreases Aβ accumulation and improves brain function in a mouse model of Aβ amyloidosis.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 34:7281-92. 2014
- RNA aptamer probes as optical imaging agents for the detection of amyloid plaques.. PloS one. 9:-. 2014
- Gene transfer of human Apoe isoforms results in differential modulation of amyloid deposition and neurotoxicity in mouse brain.. Science translational medicine. 5:-. 2013