selected publications
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academic article
- X-chromosome-wide association study for Alzheimer's disease.. Molecular psychiatry. 2024
- Report of the APOE4 National Institute on Aging/Alzheimer Disease Sequencing Project Consortium Working Group: Reducing APOE4 in Carriers is a Therapeutic Goal for Alzheimer's Disease.. Annals of Neurology. 95:625-634. 2024
- New insights into the genetic etiology of Alzheimer's disease and related dementias.. Nature genetics. 54:412-436. 2022
- Large-scale sequencing studies expand the known genetic architecture of Alzheimer's disease.. Alzheimer's & dementia (Amsterdam, Netherlands). 13:-. 2021
- Genome-wide association study and functional validation implicates JADE1 in tauopathy.. Acta neuropathologica. 143:33-53. 2021
- Current directions in tau research: Highlights from Tau 2020.. Alzheimer's & dementia : the journal of the Alzheimer's Association. 18:988-1007. 2021
- Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice.. Nature communications. 12:-. 2021
- Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.. Nature genetics. 51:1423-1424. 2019
- Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer's disease.. PloS one. 14:-. 2019
- Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.. Nature genetics. 51:414-430. 2019
- Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation.. Molecular psychiatry. 25:1859-1875. 2018
- Analysis of shared heritability in common disorders of the brain.. Science (New York, N.Y.). 360. 2018
- Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project.. Dementia and geriatric cognitive disorders. 45:1-17. 2018
- Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.. Nature genetics. 49:1373-1384. 2017
- Transethnic genome-wide scan identifies novel Alzheimer's disease loci.. Alzheimer's & dementia : the journal of the Alzheimer's Association. 13:727-738. 2017
- Two novel loci, COBL and SLC10A2, for Alzheimer's disease in African Americans.. Alzheimer's & dementia : the journal of the Alzheimer's Association. 13:119-129. 2016
- The Role of Cardiovascular Risk Factors and Stroke in Familial Alzheimer Disease.. JAMA neurology. 73:1231-1237. 2016
- Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals.. JAMA neurology. 72:1313-23. 2015
- Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk.. Alzheimer's & dementia : the journal of the Alzheimer's Association. 12:233-43. 2015
- Rarity of the Alzheimer disease-protective APP A673T variant in the United States.. JAMA neurology. 72:209-16. 2015
- Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.. JAMA neurology. 71:1394-404. 2014
- Two rare AKAP9 variants are associated with Alzheimer's disease in African Americans.. Alzheimer's & dementia : the journal of the Alzheimer's Association. 10:609-618.e11. 2014