academic article

• APOE3.  The New England journal of medicine.  390:2156-2164. 2024
• Amyloid and tau burden relate to longitudinal changes in the performance of complex everyday activities among cognitively unimpaired older adults: results from the performance-based Harvard Automated Phone Task..  Frontiers in aging neuroscience.  -. 2024
• Resilience to autosomal dominant Alzheimer's disease in a Reelin-COLBOS heterozygous man..  Nature medicine.  29:1243-1252. 2023
• Plasma biomarkers for diagnosis of Alzheimer's disease and prediction of cognitive decline in individuals with mild cognitive impairment..  Frontiers in neurology.  -. 2023
• Associations of the Harvard Automated Phone Task and Alzheimer's Disease Pathology in Cognitively Normal Older Adults: Preliminary Findings..  Journal of Alzheimer's disease : JAD.  94:217-226. 2023
• Distinct tau neuropathology and cellular profiles of an APOE3 Christchurch homozygote protected against autosomal dominant Alzheimer's dementia..  Acta neuropathologica.  144:589-601. 2022
• Menopause Status Moderates Sex Differences in Tau Burden: A Framingham PET Study..  Annals of neurology.  92:11-22. 2022
• Waning locus coeruleus integrity precedes cortical tau accrual in preclinical autosomal dominant Alzheimer's disease..  Alzheimer's & dementia : the journal of the Alzheimer's Association.  19:169-180. 2022
• Association of Carotid Intima Media Thickening with Future Brain Region Specific Amyloid-β Burden..  Journal of Alzheimer's disease : JAD.  89:223-232. 2022
• Associations Between Brainstem Volume and Alzheimer's Disease Pathology in Middle-Aged Individuals of the Framingham Heart Study..  Journal of Alzheimer's disease : JAD.  86:1603-1609. 2022
• Non-Alcoholic Fatty Liver Disease, Liver Fibrosis, and Regional Amyloid-β and Tau Pathology in Middle-Aged Adults: The Framingham Study..  Journal of Alzheimer's disease : JAD.  86:1371-1383. 2022
• In vivo rate-determining steps of tau seed accumulation in Alzheimer's disease..  Science advances.  7:-. 2021
• Current directions in tau research: Highlights from Tau 2020..  Alzheimer's & dementia : the journal of the Alzheimer's Association.  18:988-1007. 2021
• The cortical origin and initial spread of medial temporal tauopathy in Alzheimer's disease assessed with positron emission tomography..  Science translational medicine.  13. 2021
• Longitudinal amyloid and tau accumulation in autosomal dominant Alzheimer's disease: findings from the Colombia-Boston (COLBOS) biomarker study..  Alzheimer's research & therapy.  13:-. 2021
• Association of Midlife Depressive Symptoms with Regional Amyloid-β and Tau in the Framingham Heart Study..  Journal of Alzheimer's Disease.  82:249-260. 2021
• Heterogeneity of Tau Deposition and Microvascular Involvement in MCI and AD..  Current Alzheimer research.  18:711-720. 2021
• The neurophysiology and seizure outcomes of late onset unexplained epilepsy..  Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology.  131:2667-2672. 2020
• The presubiculum links incipient amyloid and tau pathology to memory function in older persons..  Neurology.  94:e1916-e1928. 2020
• Longitudinal Association of Depression Symptoms With Cognition and Cortical Amyloid Among Community-Dwelling Older Adults..  JAMA network open.  2:-. 2019
• Measuring instrumental activities of daily living in non-demented elderly: a comparison of the new performance-based Harvard Automated Phone Task with other functional assessments..  Alzheimer's research & therapy.  11:-. 2019
• Longitudinal Association of Amyloid Beta and Anxious-Depressive Symptoms in Cognitively Normal Older Adults..  The American journal of psychiatry.  175:530-537. 2018
• Association of In Vivo [18F]AV-1451 Tau PET Imaging Results With Cortical Atrophy and Symptoms in Typical and Atypical Alzheimer Disease..  JAMA neurology.  74:427-436. 2017
• Regional 18F-Fluorodeoxyglucose Hypometabolism is Associated with Higher Apathy Scores Over Time in Early Alzheimer Disease..  The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.  25:683-693. 2017
• Activities of daily living measured by the Harvard Automated Phone Task track with cognitive decline over time in non-demented elderly..  The journal of prevention of Alzheimer's disease.  4:81-86. 2017
• Depressive Symptoms and Tau Accumulation in the Inferior Temporal Lobe and Entorhinal Cortex in Cognitively Normal Older Adults: A Pilot Study..  Journal of Alzheimer's disease : JAD.  59:975-985. 2017
• Association of Higher Cortical Amyloid Burden With Loneliness in Cognitively Normal Older Adults..  JAMA psychiatry.  73:1230-1237. 2016
• Tau Positron Emission Tomographic Imaging in the Lewy Body Diseases..  JAMA neurology.  73:1334-1341. 2016
• Temporal T807 binding correlates with CSF tau and phospho-tau in normal elderly..  Neurology.  87:920-6. 2016
• Maternal dementia age at onset in relation to amyloid burden in non-demented elderly offspring..  Neurobiology of aging.  61-67. 2015
• Tau positron emission tomographic imaging in aging and early Alzheimer disease..  Annals of neurology.  79:110-9. 2015
• Validating novel tau positron emission tomography tracer [F-18]-AV-1451 (T807) on postmortem brain tissue..  Annals of neurology.  78:787-800. 2015
• Massachusetts Alzheimer's Disease Research Center: progress and challenges..  Alzheimer's & dementia : the journal of the Alzheimer's Association.  11:1241-5. 2015
• Cognitive activity relates to cognitive performance but not to Alzheimer disease biomarkers..  Neurology.  85:48-55. 2015
• Depressive Symptoms and Biomarkers of Alzheimer's Disease in Cognitively Normal Older Adults..  Journal of Alzheimer's disease : JAD.  46:63-73. 2015
• The Apathy Evaluation Scale: A Comparison of Subject, Informant, and Clinician Report in Cognitively Normal Elderly and Mild Cognitive Impairment..  Journal of Alzheimer's disease : JAD.  47:421-32. 2015
• Vascular disease and risk factors are associated with cognitive decline in the alzheimer disease spectrum..  Alzheimer disease and associated disorders.  29:18-25. 2015
• Mild to moderate Alzheimer dementia with insufficient neuropathological changes..  Annals of neurology.  75:597-601. 2014
• Subjective cognitive concerns and neuropsychiatric predictors of progression to the early clinical stages of Alzheimer disease..  The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.  22:1642-51. 2014
• Regional cortical thinning and cerebrospinal biomarkers predict worsening daily functioning across the Alzheimer's disease spectrum..  Journal of Alzheimer's disease : JAD.  41:719-28. 2014
• Regional fluorodeoxyglucose metabolism and instrumental activities of daily living across the Alzheimer's disease spectrum..  Journal of Alzheimer's disease : JAD.  42:291-300. 2014
• SIST-M-IR activities of daily living items that best discriminate clinically normal elderly from those with mild cognitive impairment..  Current Alzheimer research.  11:785-91. 2014
• Regional cortical thinning predicts worsening apathy and hallucinations across the Alzheimer disease spectrum..  The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.  22:1168-79. 2013
• Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans..  Proceedings of the National Academy of Sciences of the United States of America.  109:3985-90. 2012
• Amyloid deposition is associated with impaired default network function in older persons without dementia..  Neuron.  63:178-88. 2009