selected publications
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academic article
- APOE3. The New England journal of medicine. 390:2156-2164. 2024
- Amyloid and tau burden relate to longitudinal changes in the performance of complex everyday activities among cognitively unimpaired older adults: results from the performance-based Harvard Automated Phone Task.. Frontiers in aging neuroscience. -. 2024
- Lewy body dementia: Overcoming barriers and identifying solutions.. Alzheimer's & dementia : the journal of the Alzheimer's Association. 20:2298-2308. 2024
- Resilience to autosomal dominant Alzheimer's disease in a Reelin-COLBOS heterozygous man.. Nature medicine. 29:1243-1252. 2023
- Associations of the Harvard Automated Phone Task and Alzheimer's Disease Pathology in Cognitively Normal Older Adults: Preliminary Findings.. Journal of Alzheimer's disease : JAD. 94:217-226. 2023
- Distinct tau neuropathology and cellular profiles of an APOE3 Christchurch homozygote protected against autosomal dominant Alzheimer's dementia.. Acta neuropathologica. 144:589-601. 2022
- Menopause Status Moderates Sex Differences in Tau Burden: A Framingham PET Study.. Annals of neurology. 92:11-22. 2022
- Waning locus coeruleus integrity precedes cortical tau accrual in preclinical autosomal dominant Alzheimer's disease.. Alzheimer's & dementia : the journal of the Alzheimer's Association. 19:169-180. 2022
- Association of Carotid Intima Media Thickening with Future Brain Region Specific Amyloid-β Burden.. Journal of Alzheimer's disease : JAD. 89:223-232. 2022
- Associations Between Brainstem Volume and Alzheimer's Disease Pathology in Middle-Aged Individuals of the Framingham Heart Study.. Journal of Alzheimer's disease : JAD. 86:1603-1609. 2022
- Non-Alcoholic Fatty Liver Disease, Liver Fibrosis, and Regional Amyloid-β and Tau Pathology in Middle-Aged Adults: The Framingham Study.. Journal of Alzheimer's disease : JAD. 86:1371-1383. 2022
- The impact of COVID-19 on the well-being and cognition of older adults living in the United States and Latin America.. EClinicalMedicine. -. 2021
- The cortical origin and initial spread of medial temporal tauopathy in Alzheimer's disease assessed with positron emission tomography.. Science translational medicine. 13. 2021
- Longitudinal amyloid and tau accumulation in autosomal dominant Alzheimer's disease: findings from the Colombia-Boston (COLBOS) biomarker study.. Alzheimer's research & therapy. 13:-. 2021
- The neurophysiology and seizure outcomes of late onset unexplained epilepsy.. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. 131:2667-2672. 2020
- The presubiculum links incipient amyloid and tau pathology to memory function in older persons.. Neurology. 94:e1916-e1928. 2020
- Longitudinal Association of Depression Symptoms With Cognition and Cortical Amyloid Among Community-Dwelling Older Adults.. JAMA network open. 2:-. 2019
- Measuring instrumental activities of daily living in non-demented elderly: a comparison of the new performance-based Harvard Automated Phone Task with other functional assessments.. Alzheimer's research & therapy. 11:-. 2019
- Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer's disease.. Acta neuropathologica. 137:209-226. 2018
- The Impact of Awareness of and Concern About Memory Performance on the Prediction of Progression From Mild Cognitive Impairment to Alzheimer Disease Dementia.. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. 26:896-904. 2018
- Longitudinal Association of Amyloid Beta and Anxious-Depressive Symptoms in Cognitively Normal Older Adults.. The American journal of psychiatry. 175:530-537. 2018
- Regional 18F-Fluorodeoxyglucose Hypometabolism is Associated with Higher Apathy Scores Over Time in Early Alzheimer Disease.. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. 25:683-693. 2017
- Activities of daily living measured by the Harvard Automated Phone Task track with cognitive decline over time in non-demented elderly.. The journal of prevention of Alzheimer's disease. 4:81-86. 2017
- Depressive Symptoms and Tau Accumulation in the Inferior Temporal Lobe and Entorhinal Cortex in Cognitively Normal Older Adults: A Pilot Study.. Journal of Alzheimer's disease : JAD. 59:975-985. 2017
- Association of Higher Cortical Amyloid Burden With Loneliness in Cognitively Normal Older Adults.. JAMA psychiatry. 73:1230-1237. 2016
- Tau Positron Emission Tomographic Imaging in the Lewy Body Diseases.. JAMA neurology. 73:1334-1341. 2016
- Temporal T807 binding correlates with CSF tau and phospho-tau in normal elderly.. Neurology. 87:920-6. 2016
- The Feasibility of At-Home iPad Cognitive Testing For Use in Clinical Trials.. The journal of prevention of Alzheimer's disease. 3:8-12. 2016
- Maternal dementia age at onset in relation to amyloid burden in non-demented elderly offspring.. Neurobiology of aging. 61-67. 2015
- Tau positron emission tomographic imaging in aging and early Alzheimer disease.. Annals of neurology. 79:110-9. 2015
- Massachusetts Alzheimer's Disease Research Center: progress and challenges.. Alzheimer's & dementia : the journal of the Alzheimer's Association. 11:1241-5. 2015
- Alzheimer's disease cerebrospinal fluid biomarker in cognitively normal subjects.. Brain : a journal of neurology. 138:2701-15. 2015
- Cognitive activity relates to cognitive performance but not to Alzheimer disease biomarkers.. Neurology. 85:48-55. 2015
- Depressive Symptoms and Biomarkers of Alzheimer's Disease in Cognitively Normal Older Adults.. Journal of Alzheimer's disease : JAD. 46:63-73. 2015
- The Apathy Evaluation Scale: A Comparison of Subject, Informant, and Clinician Report in Cognitively Normal Elderly and Mild Cognitive Impairment.. Journal of Alzheimer's disease : JAD. 47:421-32. 2015
- Vascular disease and risk factors are associated with cognitive decline in the alzheimer disease spectrum.. Alzheimer disease and associated disorders. 29:18-25. 2015
- Subjective cognitive concerns, episodic memory, and the APOE ε4 allele.. Alzheimer's & dementia : the journal of the Alzheimer's Association. 10:752-759.e1. 2014
- Mild to moderate Alzheimer dementia with insufficient neuropathological changes.. Annals of neurology. 75:597-601. 2014
- Subjective cognitive concerns and neuropsychiatric predictors of progression to the early clinical stages of Alzheimer disease.. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. 22:1642-51. 2014
- Regional cortical thinning and cerebrospinal biomarkers predict worsening daily functioning across the Alzheimer's disease spectrum.. Journal of Alzheimer's disease : JAD. 41:719-28. 2014
- Regional fluorodeoxyglucose metabolism and instrumental activities of daily living across the Alzheimer's disease spectrum.. Journal of Alzheimer's disease : JAD. 42:291-300. 2014
- SIST-M-IR activities of daily living items that best discriminate clinically normal elderly from those with mild cognitive impairment.. Current Alzheimer research. 11:785-91. 2014
- Regional cortical thinning predicts worsening apathy and hallucinations across the Alzheimer disease spectrum.. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. 22:1168-79. 2013
- Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans.. Proceedings of the National Academy of Sciences of the United States of America. 109:3985-90. 2012
- Assessment of cognition in early dementia.. Alzheimer's & dementia : the journal of the Alzheimer's Association. 7:e60-e76. 2011
- Amyloid deposition is associated with impaired default network function in older persons without dementia.. Neuron. 63:178-88. 2009
- The cortical signature of Alzheimer's disease: regionally specific cortical thinning relates to symptom severity in very mild to mild AD dementia and is detectable in asymptomatic amyloid-positive individuals.. Cerebral cortex (New York, N.Y. : 1991). 19:497-510. 2008
- Clinical prediction of Alzheimer disease dementia across the spectrum of mild cognitive impairment.. Archives of general psychiatry. 64:1443-50. 2007
- Use of IQ-adjusted norms to predict progressive cognitive decline in highly intelligent older individuals.. Neuropsychology. 18:38-49. 2004
- Increased T cell reactivity to amyloid beta protein in older humans and patients with Alzheimer disease.. The Journal of clinical investigation. 112:415-22. 2003
- Use of a false recognition paradigm in an Alzheimer's disease clinical trial: a pilot study.. American journal of Alzheimer's disease and other dementias. 17:93-100. 2002