selected publications
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academic article
- Specific detection of tau seeding activity in Alzheimer's disease using rationally designed biosensor cells.. Molecular Neurodegeneration. 18:-. 2023
- Tau seeding and spreading in vivo is supported by both AD-derived fibrillar and oligomeric tau.. Acta Neuropathologica. 146:191-210. 2023
- APOE4 derived from astrocytes leads to blood-brain barrier impairment.. Brain : a journal of neurology. 145:3582-3593. 2022
- Tau propagation is dependent on the genetic background of mouse strains.. Brain communications. 4:-. 2022
- Novel genetic variants in MAPT and alterations in tau phosphorylation in amyotrophic lateral sclerosis post-mortem motor cortex and cerebrospinal fluid.. Brain pathology (Zurich, Switzerland). 32:-. 2021
- Kinetics of tau aggregation reveals patient-specific tau characteristics among Alzheimer's cases.. Brain communications. 3:-. 2021
- Continuous Monitoring of Tau-Induced Neurotoxicity in Patient-Derived iPSC-Neurons.. The Journal of Neuroscience. 41:4335-4348. 2021
- Conformational fingerprinting of tau variants and strains by Raman spectroscopy.. RSC advances. 11:8899-8915. 2021
- Author Correction: Tau molecular diversity contributes to clinical heterogeneity in Alzheimer's disease.. Nature medicine. 27:-. 2021
- Conformational fingerprinting of tau variants and strains by Raman spectroscopy. RSC Advances. 2021
- Synaptic and metabolic gene expression alterations in neurons that are recipients of proteopathic tau seeds.. Acta Neuropathologica Communications. 8:-. 2020
- Tau molecular diversity contributes to clinical heterogeneity in Alzheimer's disease.. Nature medicine. 26:1256-1263. 2020
- The Alzheimer Disease-Causing Presenilin-1 L435F Mutation Causes Increased Production of Soluble Aβ43 Species in Patient-Derived iPSC-Neurons, Closely Mimicking Matched Patient Brain Tissue.. Journal of neuropathology and experimental neurology. 79:592-604. 2020
- Tau impairs neural circuits, dominating amyloid-β effects, in Alzheimer models in vivo.. Nature Neuroscience. 22:57-64. 2018
- Tau reduction in the presence of amyloid-β prevents tau pathology and neuronal death in vivo.. Brain : a journal of neurology. 141:2194-2212. 2018
- in vitro. The Journal of biological chemistry. 293:13247-13256. 2018
- Synaptic Tau Seeding Precedes Tau Pathology in Human Alzheimer's Disease Brain.. Frontiers in neuroscience. -. 2018
- CRISPR/Cas9 Mediated Disruption of the Swedish APP Allele as a Therapeutic Approach for Early-Onset Alzheimer's Disease.. Molecular therapy. Nucleic acids. 429-440. 2018
- Tau protein liquid-liquid phase separation can initiate tau aggregation.. The EMBO journal. 37. 2018
- Characterization of TauC3 antibody and demonstration of its potential to block tau propagation.. PloS one. 12:-. 2017
- Tau Antibody Targeting Pathological Species Blocks Neuronal Uptake and Interneuron Propagation of Tau in Vitro.. The American journal of pathology. 187:1399-1412. 2017
- Seed-competent high-molecular-weight tau species accumulates in the cerebrospinal fluid of Alzheimer's disease mouse model and human patients.. Annals of neurology. 80:355-67. 2016
- Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer's disease brain.. Nature communications. -. 2015