academic article

• Specific detection of tau seeding activity in Alzheimer's disease using rationally designed biosensor cells..  Molecular Neurodegeneration.  18:-. 2023
• Tau seeding and spreading in vivo is supported by both AD-derived fibrillar and oligomeric tau..  Acta Neuropathologica.  146:191-210. 2023
• APOE4 derived from astrocytes leads to blood-brain barrier impairment..  Brain : a journal of neurology.  145:3582-3593. 2022
• Tau propagation is dependent on the genetic background of mouse strains..  Brain communications.  4:-. 2022
• Novel genetic variants in MAPT and alterations in tau phosphorylation in amyotrophic lateral sclerosis post-mortem motor cortex and cerebrospinal fluid..  Brain pathology (Zurich, Switzerland).  32:-. 2021
• Kinetics of tau aggregation reveals patient-specific tau characteristics among Alzheimer's cases..  Brain communications.  3:-. 2021
• Continuous Monitoring of Tau-Induced Neurotoxicity in Patient-Derived iPSC-Neurons..  The Journal of Neuroscience.  41:4335-4348. 2021
• Conformational fingerprinting of tau variants and strains by Raman spectroscopy..  RSC advances.  11:8899-8915. 2021
• Author Correction: Tau molecular diversity contributes to clinical heterogeneity in Alzheimer's disease..  Nature medicine.  27:-. 2021
• Conformational fingerprinting of tau variants and strains by Raman spectroscopy.  RSC Advances.  2021
• Synaptic and metabolic gene expression alterations in neurons that are recipients of proteopathic tau seeds..  Acta Neuropathologica Communications.  8:-. 2020
• Tau molecular diversity contributes to clinical heterogeneity in Alzheimer's disease..  Nature medicine.  26:1256-1263. 2020
• The Alzheimer Disease-Causing Presenilin-1 L435F Mutation Causes Increased Production of Soluble Aβ43 Species in Patient-Derived iPSC-Neurons, Closely Mimicking Matched Patient Brain Tissue..  Journal of neuropathology and experimental neurology.  79:592-604. 2020
• Tau impairs neural circuits, dominating amyloid-β effects, in Alzheimer models in vivo..  Nature Neuroscience.  22:57-64. 2018
• Tau reduction in the presence of amyloid-β prevents tau pathology and neuronal death in vivo..  Brain : a journal of neurology.  141:2194-2212. 2018
• in vitro.  The Journal of biological chemistry.  293:13247-13256. 2018
• Synaptic Tau Seeding Precedes Tau Pathology in Human Alzheimer's Disease Brain..  Frontiers in neuroscience.  -. 2018
• CRISPR/Cas9 Mediated Disruption of the Swedish APP Allele as a Therapeutic Approach for Early-Onset Alzheimer's Disease..  Molecular therapy. Nucleic acids.  429-440. 2018
• Tau protein liquid-liquid phase separation can initiate tau aggregation..  The EMBO journal.  37. 2018
• Characterization of TauC3 antibody and demonstration of its potential to block tau propagation..  PloS one.  12:-. 2017
• Tau Antibody Targeting Pathological Species Blocks Neuronal Uptake and Interneuron Propagation of Tau in Vitro..  The American journal of pathology.  187:1399-1412. 2017
• Seed-competent high-molecular-weight tau species accumulates in the cerebrospinal fluid of Alzheimer's disease mouse model and human patients..  Annals of neurology.  80:355-67. 2016
• Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer's disease brain..  Nature communications.  -. 2015