selected publications
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academic article
- Multifaceted roles of APOE in Alzheimer disease.. Nature Reviews Neurology. 20:457-474. 2024
- APOE2 gene therapy reduces amyloid deposition and improves markers of neuroinflammation and neurodegeneration in a mouse model of Alzheimer disease.. Molecular therapy : the journal of the American Society of Gene Therapy. 32:1373-1386. 2024
- Astrocyte tau deposition in progressive supranuclear palsy is associated with dysregulation of MAPT transcription. Acta Neuropathologica Communications. 2024
- APOE4 derived from astrocytes leads to blood-brain barrier impairment.. Brain : a journal of neurology. 145:3582-3593. 2022
- APOE. Nature Aging. 1:919-931. 2021
- Apolipoprotein E4 Reduction with Antisense Oligonucleotides Decreases Neurodegeneration in a Tauopathy Model.. Annals of neurology. 89:952-966. 2021
- Opposing Roles of apolipoprotein E in aging and neurodegeneration.. Life science alliance. 2. 2019
- Human tau increases amyloid β plaque size but not amyloid β-mediated synapse loss in a novel mouse model of Alzheimer's disease.. The European journal of neuroscience. 44:3056-3066. 2016