selected publications
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academic article
- Differential regulation of brain microvessel transcriptome and brain metabolome by western and heart-healthy dietary patterns in Ossabaw pigs.. Scientific reports. 14:-. 2024
- Astrocyte transcriptomic changes along the spatiotemporal progression of Alzheimer's disease.. Nature neuroscience. 27:2384-2400. 2024
- Neurofibrillary tangle-bearing neurons have reduced risk of cell death in mice with Alzheimer's pathology.. Cell reports. 43:-. 2024
- Landscape of brain myeloid cell transcriptome along the spatiotemporal progression of Alzheimer's disease reveals distinct sequential responses to Aβ and tau.. Acta neuropathologica. 147:-. 2024
- Brain Vasculature Accumulates Tau and Is Spatially Related to Tau Tangle Pathology in Alzheimer's Disease.. Acta neuropathologica. 147:-. 2024
- Specific detection of tau seeding activity in Alzheimer's disease using rationally designed biosensor cells.. Molecular Neurodegeneration. 18:-. 2023
- Endothelial Cells Are Heterogeneous in Different Brain Regions and Are Dramatically Altered in Alzheimer's Disease.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 43:4541-4557. 2023
- Spatial characterization of tangle-bearing neurons and ghost tangles in the human inferior temporal gyrus with three-dimensional imaging.. Brain communications. 5:-. 2023
- Tissue libraries enable rapid determination of conditions that preserve antibody labeling in cleared mouse and human tissue.. eLife. 2023
- APOE4 derived from astrocytes leads to blood-brain barrier impairment.. Brain : a journal of neurology. 145:3582-3593. 2022
- Continuous Monitoring of Tau-Induced Neurotoxicity in Patient-Derived iPSC-Neurons.. The Journal of Neuroscience. 41:4335-4348. 2021
- Heterogeneity of Tau Deposition and Microvascular Involvement in MCI and AD.. Current Alzheimer research. 18:711-720. 2021
- Synaptic and metabolic gene expression alterations in neurons that are recipients of proteopathic tau seeds.. Acta Neuropathologica Communications. 8:-. 2020
- Cerebrovascular Senescence Is Associated With Tau Pathology in Alzheimer's Disease.. Frontiers in neurology. -. 2020
- Tau reduction in aged mice does not impact Microangiopathy.. Acta neuropathologica communications. 8:-. 2020
- PTEN activation contributes to neuronal and synaptic engulfment by microglia in tauopathy.. Acta neuropathologica. 140:7-24. 2020
- Experimental evidence for the age dependence of tau protein spread in the brain.. Science advances. 5:-. 2019
- Partial reduction of microglia does not affect tau pathology in aged mice.. Journal of neuroinflammation. 15:-. 2018
- Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease.. Neuron. 99:925-940.e7. 2018
- Tau reduction in the presence of amyloid-β prevents tau pathology and neuronal death in vivo.. Brain : a journal of neurology. 141:2194-2212. 2018
- Tau protein liquid-liquid phase separation can initiate tau aggregation.. The EMBO journal. 37. 2018
- Tau induces blood vessel abnormalities and angiogenesis-related gene expression in P301L transgenic mice and human Alzheimer's disease.. Proceedings of the National Academy of Sciences of the United States of America. 115:E1289-E1298. 2018
- Studying tau protein propagation and pathology in the mouse brain using adeno-associated viruses.. Methods in cell biology. 307-322. 2017
- Characterization of TauC3 antibody and demonstration of its potential to block tau propagation.. PloS one. 12:-. 2017
- Enhanced Tau Aggregation in the Presence of Amyloid β.. The American journal of pathology. 187:1601-1612. 2017
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