selected publications
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academic article
- Alzheimer proteopathic tau seeds are biochemically a forme fruste of mature paired helical filaments.. Brain : a journal of neurology. 147:637-648. 2024
- Rate of tau propagation is a heritable disease trait in genetically diverse mouse strains.. iScience. 26:-. 2023
- Tau propagation is dependent on the genetic background of mouse strains.. Brain communications. 4:-. 2022
- Novel genetic variants in MAPT and alterations in tau phosphorylation in amyotrophic lateral sclerosis post-mortem motor cortex and cerebrospinal fluid.. Brain pathology (Zurich, Switzerland). 32:-. 2021
- Targeting Tau Mitigates Mitochondrial Fragmentation and Oxidative Stress in Amyotrophic Lateral Sclerosis.. Molecular neurobiology. 59:683-702. 2021
- Impact of Sterilization Methods on the Seeding Ability of Human Tau Proteopathic Seeds.. Journal of neuropathology and experimental neurology. 80:912-921. 2021
- Kinetics of tau aggregation reveals patient-specific tau characteristics among Alzheimer's cases.. Brain communications. 3:-. 2021
- Regulation of tau internalization, degradation, and seeding by LRP1 reveals multiple pathways for tau catabolism.. The Journal of biological chemistry. -. 2021
- Continuous Monitoring of Tau-Induced Neurotoxicity in Patient-Derived iPSC-Neurons.. The Journal of Neuroscience. 41:4335-4348. 2021
- Author Correction: Tau molecular diversity contributes to clinical heterogeneity in Alzheimer's disease.. Nature medicine. 27:-. 2021
- A multifactorial model of pathology for age of onset heterogeneity in familial Alzheimer's disease.. Acta neuropathologica. 141:217-233. 2020
- Tau PTM Profiles Identify Patient Heterogeneity and Stages of Alzheimer's Disease.. Cell. 183:1699-1713.e13. 2020
- Synaptic and metabolic gene expression alterations in neurons that are recipients of proteopathic tau seeds.. Acta Neuropathologica Communications. 8:-. 2020
- Tau reduction in aged mice does not impact Microangiopathy.. Acta neuropathologica communications. 8:-. 2020
- Tau molecular diversity contributes to clinical heterogeneity in Alzheimer's disease.. Nature medicine. 26:1256-1263. 2020
- Tau Prion-Like Propagation: State of the Art and Current Challenges.. Advances in experimental medicine and biology. 305-325. 2019
- Tau impairs neural circuits, dominating amyloid-β effects, in Alzheimer models in vivo.. Nature Neuroscience. 22:57-64. 2018
- Different tau species lead to heterogeneous tau pathology propagation and misfolding.. Acta neuropathologica communications. 6:-. 2018
- Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease.. Neuron. 99:925-940.e7. 2018
- Tau reduction in the presence of amyloid-β prevents tau pathology and neuronal death in vivo.. Brain : a journal of neurology. 141:2194-2212. 2018
- Tau protein liquid-liquid phase separation can initiate tau aggregation.. The EMBO journal. 37. 2018
- Enhanced Tau Aggregation in the Presence of Amyloid β.. The American journal of pathology. 187:1601-1612. 2017