selected publications
-
academic article
- Astrocyte transcriptomic changes along the spatiotemporal progression of Alzheimer's disease.. Nature neuroscience. 27:2384-2400. 2024
- Landscape of brain myeloid cell transcriptome along the spatiotemporal progression of Alzheimer's disease reveals distinct sequential responses to Aβ and tau.. Acta neuropathologica. 147:-. 2024
- Cryptic splicing of stathmin-2 and UNC13A mRNAs is a pathological hallmark of TDP-43-associated Alzheimer's disease.. Acta neuropathologica. 147:-. 2024
- Alzheimer DataLENS: An Open Data Analytics Portal for Alzheimer's Disease Research.. Journal of Alzheimer's disease : JAD. 99:S397-S407. 2024
- Distinct transcriptomic responses to Aβ plaques, neurofibrillary tangles, and APOE in Alzheimer's disease.. Alzheimer's & dementia : the journal of the Alzheimer's Association. 20:74-90. 2023
- Endothelial Cells Are Heterogeneous in Different Brain Regions and Are Dramatically Altered in Alzheimer's Disease.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 43:4541-4557. 2023
- Plasma biomarkers for diagnosis of Alzheimer's disease and prediction of cognitive decline in individuals with mild cognitive impairment.. Frontiers in neurology. -. 2023
- APOE. Neurology Genetics. 9:-. 2023
- Causal inference in medical records and complementary systems pharmacology for metformin drug repurposing towards dementia.. Nature communications. 13:-. 2022
- Development and Evaluation of a Natural Language Processing Annotation Tool to Facilitate Phenotyping of Cognitive Status in Electronic Health Records: Diagnostic Study.. Journal of medical Internet research. 24:-. 2022
- Plasma biomarkers for prognosis of cognitive decline in patients with mild cognitive impairment.. Brain communications. 4:-. 2022
- Technical Performance Evaluation of Olink Proximity Extension Assay for Blood-Based Biomarker Discovery in Longitudinal Studies of Alzheimer's Disease.. Frontiers in neurology. -. 2022
- Cyclic multiplex fluorescent immunohistochemistry and machine learning reveal distinct states of astrocytes and microglia in normal aging and Alzheimer's disease.. Journal of neuroinflammation. 19:-. 2022
- Systematic review of human post-mortem immunohistochemical studies and bioinformatics analyses unveil the complexity of astrocyte reaction in Alzheimer's disease.. Neuropathology and applied neurobiology. 48:-. 2021
- Visit-to-Visit Blood Pressure Variability, Neuropathology, and Cognitive Decline.. Neurology. 96:e2812-e2823. 2021
- Synaptic proteins associated with cognitive performance and neuropathology in older humans revealed by multiplexed fractionated proteomics.. Neurobiology of aging. 99-114. 2021
- APOE. Nature Aging. 1:919-931. 2021
- Differential gene expression data from the human central nervous system across Alzheimer's disease, Lewy body diseases, and the amyotrophic lateral sclerosis and frontotemporal dementia spectrum.. Data in brief. -. 2021
- APOE and Alzheimer's disease: advances in genetics, pathophysiology, and therapeutic approaches.. The Lancet. Neurology. 20:68-80. 2021
- Systematic review and meta-analysis of human transcriptomics reveals neuroinflammation, deficient energy metabolism, and proteostasis failure across neurodegeneration.. Neurobiology of disease. -. 2020
- Cerebrovascular Senescence Is Associated With Tau Pathology in Alzheimer's Disease.. Frontiers in neurology. -. 2020
- Meta-analysis of mouse transcriptomic studies supports a context-dependent astrocyte reaction in acute CNS injury versus neurodegeneration.. Journal of neuroinflammation. 17:-. 2020
- Characterizing Clinical and Neuropathological Traits of APOE Haplotypes in African Americans and Europeans.. Journal of Alzheimer's disease : JAD. 78:467-477. 2020
- Characterization of the 18 kDa translocator protein (TSPO) expression in post-mortem normal and Alzheimer's disease brains.. Brain pathology (Zurich, Switzerland). 30:151-164. 2019
- The Major Risk Factors for Alzheimer's Disease: Age, Sex, and Genes Modulate the Microglia Response to Aβ Plaques.. Cell reports. 27:1293-1306.e6. 2019
- Novel methods for integration and visualization of genomics and genetics data in Alzheimer's disease.. Alzheimer's & dementia : the journal of the Alzheimer's Association. 15:788-798. 2019
- Neuronal calcineurin transcriptional targets parallel changes observed in Alzheimer disease brain.. Journal of neurochemistry. 147:24-39. 2018
- Tau induces blood vessel abnormalities and angiogenesis-related gene expression in P301L transgenic mice and human Alzheimer's disease.. Proceedings of the National Academy of Sciences of the United States of America. 115:E1289-E1298. 2018