HIV induces synaptic hyperexcitation via cGMP-dependent protein kinase II activation in the FIV infection model.
Academic Article
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Overview
publication date
- July 27, 2018
has subject area
- Animals
- Calcium
- Cats
- Chemokine CXCL12
- Cyclic GMP-Dependent Protein Kinase Type II
- Disease Models, Animal
- Enzyme Activation
- Feline Acquired Immunodeficiency Syndrome
- HIV Envelope Protein gp120
- HIV-1
- Hippocampus
- Immunodeficiency Virus, Feline
- Inositol 1,4,5-Trisphosphate Receptors
- Mice
- Models, Biological
- Neurons
- Nitric Oxide Synthase Type I
- Protein Subunits
- Receptors, AMPA
- Synapses
- Viral Proteins
published in
- PLoS biology Journal