Publications in VIVO

Co-author Network

Co-investigator Network

Aparicio, Hugo, MD, MPH

Associate Professor of Neurology

positions

center affiliation
- CLRC PI, Massachusetts Center for Alzheimer and dEmeNtia behaVIoral reSearch In minOrity aging (Mass-ENVISION) 2023 -
institutional affiliation
- Associate Professor of Neurology, Boston University Chobanian & Avedisian School of Medicine 2016 -

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selected publications

academic article
- Association of Plasma YKL-40 With MRI, CSF, and Cognitive Markers of Brain Health and Dementia. Neurology. 2024
- Optimal blood tau species for the detection of Alzheimer's disease neuropathology: an immunoprecipitation mass spectrometry and autopsy study.. Acta neuropathologica. 147:-. 2023
- Cross-sectional and longitudinal evaluation of plasma glial fibrillary acidic protein to detect and predict clinical syndromes of Alzheimer's disease.. Alzheimer's & dementia (Amsterdam, Netherlands). 15:-. 2023
- Hypertension Trends and White Matter Brain Injury in the Offspring Framingham Heart Study Cohort.. Hypertension. 81:87-95. 2023
- The association of circulating endocannabinoids with neuroimaging and blood biomarkers of neuro-injury.. Alzheimer's research & therapy. 15:-. 2023
- Healthy Lifestyle for Healthier Arteries in People With Type 2 Diabetes.. Journal of the American Heart Association. 12:-. 2023
- Association between dietary inflammatory index score and incident dementia: results from the Framingham heart Study offspring cohort.. medRxiv : the preprint server for health sciences. 2023
- Strokes in Patients With Injection Drug Use and Tricuspid Valve Endocarditis - A Case Series.. The Neurohospitalist. 13:272-277. 2023
- Cognitive Impairment After Ischemic and Hemorrhagic Stroke: A Scientific Statement From the American Heart Association/American Stroke Association.. Stroke. 54:e272-e291. 2023
- Secular Trends in Head Size and Cerebral Volumes In the Framingham Heart Study for Birth Years 1902-1985.. Research square. 2023
- Antiplatelet Therapy or Not for Asymptomatic/Incidental Lacunar Infarction. Stroke. 2023
- Association of MRI Visible Perivascular Spaces and Neurofilament Light Chain: The Framingham Heart Study.. Journal of Alzheimer's disease : JAD. 95:1133-1145. 2023
- MRI Visible Perivascular Spaces and the Risk of Incident Mild Cognitive Impairment in a Community Sample.. Journal of Alzheimer's disease : JAD. 96:103-112. 2023
- Association of Red Blood Cell Omega-3 Fatty Acids With MRI Markers and Cognitive Function in Midlife: The Framingham Heart Study.. Neurology. 99:e2572-e2582. 2022
- MRI-Visible Perivascular Spaces and Risk of Incident Dementia: The Framingham Heart Study.. Neurology. 99:e2561-e2571. 2022
- Ante-mortem plasma phosphorylated tau (181) predicts Alzheimer's disease neuropathology and regional tau at autopsy.. Brain : a journal of neurology. 145:3546-3557. 2022
- Outcome Prediction in Cerebral Venous Thrombosis: The IN-REvASC Score.. Journal of stroke. 24:404-416. 2022
- Predictors of Recurrent Venous Thrombosis After Cerebral Venous Thrombosis: Analysis of the ACTION-CVT Study.. Neurology. 99:e2368-e2377. 2022
- A population-based meta-analysis of circulating GFAP for cognition and dementia risk.. Annals of clinical and translational neurology. 9:1574-1585. 2022
- Racial and Ethnic Differences in Short- and Long-term Mortality by Stroke Type.. Neurology. 98:e2465-e2473. 2022
- Egg consumption and risk of acute stroke in the Million Veteran Program.. Clinical Nutrition ESPEN. 178-182. 2022
- Relations of Metabolic Health and Obesity to Brain Aging in Young to Middle-Aged Adults.. Journal of the American Heart Association. 11:-. 2022
- Use of Marijuana: Effect on Brain Health: A Scientific Statement From the American Heart Association.. Stroke. 53:e176-e187. 2022
- Association of Loneliness With 10-Year Dementia Risk and Early Markers of Vulnerability for Neurocognitive Decline.. Neurology. 98:e1337-e1348. 2022
- Low Blood Pressure, Comorbidities, and Ischemic Stroke Mortality in US Veterans.. Stroke. 53:886-894. 2021
- Digital Peripheral Arterial Tonometry and Cardiovascular Disease Events: The Framingham Heart Study.. Stroke. 52:2866-2873. 2021
- A Primary Care Agenda for Brain Health: A Scientific Statement From the American Heart Association.. Stroke. 52:e295-e308. 2021
- Systemic inflammation as a moderator between sleep and incident dementia.. Sleep. 44. 2021
- Stroke etiologies in patients with COVID-19: the SVIN COVID-19 multinational registry.. BMC Neurology. 21:-. 2021
- Heart Disease and Stroke Statistics-2021 Update: A Report From the American Heart Association.. Circulation. 143:e254-e743. 2021
- Incidence of Transient Ischemic Attack and Association With Long-term Risk of Stroke.. JAMA. 325:373-381. 2021
- A Primary Care Agenda for Brain Health: A Scientific Statement From the American Heart Association. Stroke. 2021
- Association of Midlife Depressive Symptoms with Regional Amyloid-β and Tau in the Framingham Heart Study.. Journal of Alzheimer's Disease. 82:249-260. 2021
- Digital Peripheral Arterial Tonometry and Cardiovascular Disease Events. Stroke. 2021
- Heart Disease and Stroke Statistics—2021 Update: A Report From the American Heart Association. Circulation. 2021
- Herpes Labialis, Chlamydophila pneumoniae, Helicobacter pylori, and Cytomegalovirus Infections and Risk of Dementia: The Framingham Heart Study.. Journal of Alzheimer's Disease. 82:593-605. 2021
- Higher dietary inflammatory index scores are associated with increased incidence of all‐cause dementia in the Framingham Heart Study. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2021
- Interleukin-6 Interacts with Sleep Apnea Severity when Predicting Incident Alzheimer's Disease Dementia.. Journal of Alzheimer's Disease. 2021
- Interleukin-6 Interacts with Sleep Apnea Severity when Predicting Incident Alzheimer's Disease Dementia.. Journal of Alzheimer's disease : JAD. 79:1451-1457. 2021
- Questionnaire and Portable Sleep Test Screening of Sleep Disordered Breathing in Acute Stroke and TIA. Journal of Clinical Medicine. 2021
- Stroke Prevention in Patients with Patent Foramen Ovale. Current Cardiology Reports. 2021
- Decline in mild stroke presentations and intravenous thrombolysis during the COVID-19 pandemic: The Society of Vascular and Interventional Neurology Multicenter Collaboration.. Clinical Neurology and Neurosurgery. -. 2020
- Cerebral Venous Sinus Thromboses in Patients with SARS-CoV-2 Infection: Three Cases and a Review of the Literature.. Journal of Stroke and Cerebrovascular Diseases. 29:-. 2020
- Chronic Kidney Disease as Risk Factor for Enlarged Perivascular Spaces in Patients With Stroke and Relation to Racial Group.. Stroke. 51:3348-3351. 2020
- Assessment of Incidence and Risk Factors of Intracerebral Hemorrhage Among Participants in the Framingham Heart Study Between 1948 and 2016.. JAMA Neurology. 77:1252-1260. 2020
- Exome Array Analysis of Early-Onset Ischemic Stroke.. Stroke. 51:3356-3360. 2020
- Decline in stroke alerts and hospitalisations during the COVID-19 pandemic.. Stroke and vascular neurology. 5:403-405. 2020
- Mid to Late Life Hypertension Trends and Cerebral Small Vessel Disease in the Framingham Heart Study.. Hypertension (Dallas, Tex. : 1979). 76:707-714. 2020
- Optimization of resources and modifications in acute ischemic stroke care in response to the global COVID-19 pandemic.. Journal of Stroke and Cerebrovascular Diseases. 29:-. 2020
- Abstract MP28: Egg Consumption is Positively Associated With Ischemic Stroke: The Million Veteran Program. Circulation. 2020
- Abstract P255: Moderate Alcohol Consumption and the Risk of Acute Ischemic Stroke and All-Cause Mortality: The Million Veteran Program. Circulation. 2020
- Exome Array Analysis of Early-Onset Ischemic Stroke. Stroke. 2020
- Mid to Late Life Hypertension Trends and Cerebral Small Vessel Disease in the Framingham Heart Study. Hypertension. 2020
- Plasma YKL40 as a biomarker for brain aging and injury in three community cohorts. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2020
- Revised Framingham Stroke Risk Profile: Association with Cognitive Status and MRI-Derived Volumetric Measures.. Journal of Alzheimer's Disease. 78:1393-1408. 2020
- Association of CD14 with incident dementia and markers of brain aging and injury.. Neurology. 94:e254-e266. 2019
- Response by Aparicio et al to Letter Regarding Article, "Temporal Trends in Ischemic Stroke Incidence in Younger Adults in the Framingham Study".. Stroke. 50:-. 2019
- Whole blood microRNA expression associated with stroke: Results from the Framingham Heart Study.. PloS one. 14:-. 2019
- Plasma total-tau as a biomarker of stroke risk in the community.. Annals of neurology. 86:463-467. 2019
- Temporal Trends in Ischemic Stroke Incidence in Younger Adults in the Framingham Study.. Stroke. 50:1558-1560. 2019
- Assessment of Plasma Total Tau Level as a Predictive Biomarker for Dementia and Related Endophenotypes.. JAMA neurology. 76:598-606. 2019
- Stroke Research With Longitudinal Cohort Studies.. Stroke. 50:e103-e105. 2019
- Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting.. Neurology. 92:e486-e503. 2019
- Serum magnesium and calcium levels in relation to ischemic stroke: Mendelian randomization study.. Neurology. 92:e944-e950. 2019
- Abstract P405: Racial Disparities in Ischemic and Hemorrhagic Post-stroke Mortality in United States Veterans. Circulation. 2019
- Abstract TMP55: Abdominal Obesity Predicts Stroke Risk in the Framingham Study. Stroke. 2019
- Abstract TP206: Prevalence and Predictors of Cerebral Microbleeds Among Racial Minorities With Ischemic Stroke and Transient Ischemic Attack. Stroke. 2019
- Abstract TP425: Prevalence and Predictors of Cortical Superficial Siderosis Among African Americans with Ischemic Stroke and Transient Ischemic Attack. Stroke. 2019
- Abstract WP211: Exome Association Analysis of Small Vessel Young Onset Ischemic Stroke. Stroke. 2019
- Abstract WP221: Relation Between Blood Pressure and Stroke Mortality in the United States Veteran Population. Stroke. 2019
- Abstract WP249: Illicit Drug Use and Cerebral Microbleeds in Stroke and Transient Ischemic Attack Patients. Stroke. 2019
- Response by Aparicio et al to Letter Regarding Article, "Temporal Trends in Ischemic Stroke Incidence in Younger Adults in the Framingham Study".. Stroke. 2019
- APOE and the Association of Fatty Acids With the Risk of Stroke, Coronary Heart Disease, and Mortality.. Stroke. 49:2822-2829. 2018
- Vascular risk at younger ages most strongly associates with current and future brain volume.. Neurology. 91:e1479-e1486. 2018
- Author response: Sleep architecture and the risk of incident dementia in the community.. Neurology. 90:-. 2018
- Abstract 171: Endothelial Microparticle Levels and Silent Stroke in the Framingham Heart Study. Stroke. 2018
- Abstract WMP49: Epidemiology of Transient Ischemic Attacks and Risk of Stroke in the Community-The Framingham Study. Stroke. 2018
- Abstract WP160: Exome Array Analysis of Early-Onset Ischemic Stroke. Stroke. 2018
- Abstract WP170: Chronic Kidney Disease as a Risk Factor for Enlarged Perivascular Spaces, and Relation to Racial Group. Stroke. 2018
- Abstract WP189: Prevalence and Risk Factors for Cerebral Enlarged Perivascular Spaces in Relation to Race and Stroke Severity. Stroke. 2018
- Sleep architecture and the risk of incident dementia in the community.. Neurology. 89:1244-1250. 2017
- Overweight, Obesity, and Survival After Stroke in the Framingham Heart Study.. Journal of the American Heart Association. 6. 2017
- Association of descending thoracic aortic plaque with brain atrophy and white matter hyperintensities: The Framingham Heart Study.. Atherosclerosis. 305-311. 2017
- Sugar- and Artificially Sweetened Beverages and the Risks of Incident Stroke and Dementia: A Prospective Cohort Study.. Stroke. 48:1139-1146. 2017
- Associations between social relationship measures, serum brain-derived neurotrophic factor, and risk of stroke and dementia.. Alzheimer's & dementia (New York, N. Y.). 3:229-237. 2017
- Sugary beverage intake and preclinical Alzheimer's disease in the community.. Alzheimer's & dementia : the journal of the Alzheimer's Association. 13:955-964. 2017
- Revised Framingham Stroke Risk Profile to Reflect Temporal Trends.. Circulation. 135:1145-1159. 2017
- Stroke as the Initial Manifestation of Atrial Fibrillation: The Framingham Heart Study.. Stroke. 48:490-492. 2017
- Abstract 56: An Exome Array Analysis of Ischemic Stroke in the Genetics of Early Onset Stroke Study. Stroke. 2017
- Overweight, Obesity, and Survival After Stroke in the Framingham Heart Study. Journal of the American Heart Association. 2017
- Revised Framingham Stroke Risk Profile to Reflect Temporal TrendsClinical Perspective. Circulation. 2017
- [O3–05–06]: REM SLEEP MECHANISMS PREDICT INCIDENT DEMENTIA IN THE FRAMINGHAM HEART STUDY. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2017
- Lacunar Infarcts and Intracerebral Hemorrhage Differences: A Nested Case-Control Analysis in the FHS (Framingham Heart Study).. Stroke. 48:486-489. 2016
- Association of Ideal Cardiovascular Health With Vascular Brain Injury and Incident Dementia.. Stroke. 47:1201-6. 2016
- Identification of additional risk loci for stroke and small vessel disease: a meta-analysis of genome-wide association studies.. The Lancet Neurology. 15:695-707. 2016
- Abstract 41: Stroke Unit Evaluation of Sleep Apnea: Validity of Screening Tools and Use of a Portable Sleep Study. Stroke. 2016
- Differences Between Lacunar Infarcts and Deep Intracerebral hemorrhage: A Nested Case-Control Study from the Framingham Heart Study (S121). Annals of Neurology. 2016
- The Effect of Language Barriers on Door-to-Needle Times for IV Thrombolysis Administration in Acute Stroke Patients (P1.266). Neurology. 2016
- Interarm differences in systolic blood pressure and the risk of dementia and subclinical brain injury.. Alzheimer's & dementia : the journal of the Alzheimer's Association. 12:438-45. 2015
- Racial Disparities in Intravenous Recombinant Tissue Plasminogen Activator Use Persist at Primary Stroke Centers.. J Am Heart Assoc. 4:-. 2015
- Heart of the Matter.. Stroke. 46:1755-6. 2015
- Congenital Trypanosoma cruzi transmission in Santa Cruz, Bolivia. Clin Infect Dis. 2009
- Polymerase chain reaction for chronic Trypanosoma cruzi infection yields higher sensitivity in blood clot than buffy coat or whole blood specimens. Am J Trop Med Hyg. 2008
- O2‐05‐02: IMPACT OF AGE ON THE ASSOCIATION BETWEEN VASCULAR RISK FACTOR BURDEN AND BRAIN VOLUME. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2006
- Race and Science: Using a Comprehensive Interdisciplinary Approach to Address Complex Issues. College Teaching. 2003
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