Pharmacological inhibition of PARP-1 reduces alpha-synuclein- and MPP+-induced cytotoxicity in Parkinson's disease in vitro models.
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Overview
publication date
- April 5, 2007
has subject area
- 1-Methyl-4-phenylpyridinium
- Cell Nucleus
- Cell Survival
- Cells, Cultured
- Cytoplasm
- Dopamine
- Dose-Response Relationship, Drug
- Enzyme Inhibitors
- Humans
- Molecular Structure
- Neurons
- Neuroprotective Agents
- Parkinson Disease
- Phenanthrenes
- Poly (ADP-Ribose) Polymerase-1
- Poly(ADP-ribose) Polymerase Inhibitors
- alpha-Synuclein